San Francisco
49ers
Levi's StadiumSep 10
@ Pittsburgh SteelersW 30–7Sep 17
@ Los Angeles RamsW 30–23Sep 21
vs New York GiantsW 30–12Oct 1
vs Arizona CardinalsW 35–16Oct 8
vs Dallas CowboysW 42–10Oct 15
@ Cleveland BrownsL 17–19Oct 23
@ Minnesota VikingsL 17–22Oct 29
vs Cincinnati BengalsL 17–31Nov 12
@ Jacksonville JaguarsW 34–3Nov 19
vs Tampa Bay BuccaneersW 27–14Nov 23
@ Seattle SeahawksW 31–13Dec 3
@ Philadelphia EaglesW 42–19Dec 10vs Seattle SeahawksW 28–16Dec 17@ Arizona CardinalsW 45–29Dec 25
vs Baltimore RavensL 19–33Dec 31
@ Washington CommandersW 27–10Jan 7vs Los Angeles RamsL 20–21Jan 20
vs Green Bay PackersPOSTW 24–21Jan 28
vs Detroit LionsPOSTW 34–31Feb 11
@ Kansas City ChiefsPOSTL 22–25
@ Pittsburgh SteelersW 30–7Sep 17@ Los Angeles RamsW 30–23Sep 21vs New York GiantsW 30–12Oct 1vs Arizona CardinalsW 35–16Oct 8vs Dallas CowboysW 42–10Oct 15@ Cleveland BrownsL 17–19Oct 23@ Minnesota VikingsL 17–22Oct 29vs Cincinnati BengalsL 17–31Nov 12@ Jacksonville JaguarsW 34–3Nov 19vs Tampa Bay BuccaneersW 27–14Nov 23@ Seattle SeahawksW 31–13Dec 3@ Philadelphia EaglesW 42–19Dec 10vs Seattle SeahawksW 28–16Dec 17@ Arizona CardinalsW 45–29Dec 25vs Baltimore RavensL 19–33Dec 31@ Washington CommandersW 27–10Jan 7vs Los Angeles RamsL 20–21Jan 20vs Green Bay PackersPOSTW 24–21Jan 28vs Detroit LionsPOSTW 34–31Feb 11@ Kansas City ChiefsPOSTL 22–25