San Francisco
49ers
Levi's StadiumSep 9
@ Minnesota VikingsL 16–24Sep 16
vs Detroit LionsW 30–27Sep 23
@ Kansas City ChiefsL 27–38Sep 30
@ Los Angeles ChargersL 27–29Oct 7
vs Arizona CardinalsL 18–28Oct 15
@ Green Bay PackersL 30–33Oct 21
vs Los Angeles RamsL 10–39Oct 28@ Arizona CardinalsL 15–18Nov 1
vs Oakland RaidersW 34–3Nov 12
vs New York GiantsL 23–27Nov 25
@ Tampa Bay BuccaneersL 9–27Dec 2
@ Seattle SeahawksL 16–43Dec 9
vs Denver BroncosW 20–14Dec 16vs Seattle SeahawksW 26–23Dec 23
vs Chicago BearsL 9–14Dec 30@ Los Angeles RamsL 32–48
@ Minnesota VikingsL 16–24Sep 16vs Detroit LionsW 30–27Sep 23@ Kansas City ChiefsL 27–38Sep 30@ Los Angeles ChargersL 27–29Oct 7vs Arizona CardinalsL 18–28Oct 15@ Green Bay PackersL 30–33Oct 21vs Los Angeles RamsL 10–39Oct 28@ Arizona CardinalsL 15–18Nov 1vs Oakland RaidersW 34–3Nov 12vs New York GiantsL 23–27Nov 25@ Tampa Bay BuccaneersL 9–27Dec 2@ Seattle SeahawksL 16–43Dec 9vs Denver BroncosW 20–14Dec 16vs Seattle SeahawksW 26–23Dec 23vs Chicago BearsL 9–14Dec 30@ Los Angeles RamsL 32–48