Russell Wilson · Roost| Dec 13 | @ BAL | W 35-6 | 23 | 32 | 292 | 71.9 | 9.1 | 5 | 0 | 49 | 0 | 139.6 | 96.4 | 1 | 6 | 6.0 | 0 | 6 |
| Dec 6 | @ MIN | W 38-7 | 21 | 27 | 274 | 77.8 | 10.1 | 3 | 0 | 53 | 1 | 146.0 | 94.2 | 9 | 51 | 5.7 | 1 | 14 |
| Nov 29 | vs PIT | W 39-30 | 21 | 30 | 345 | 70.0 | 11.5 | 5 | 0 | 80 | 2 | 147.9 | 79.0 | 4 | 14 | 3.5 | 0 | 10 |
| Nov 22 | vs SF | W 29-13 | 24 | 29 | 260 | 82.8 | 9.0 | 3 | 0 | 31 | 2 | 138.5 | 85.8 | 9 | 30 | 3.3 | 0 | 8 |
| Nov 15 | vs ARI | L 39-32 | 14 | 32 | 240 | 43.8 | 7.5 | 1 | 1 | 40 | 2 | 67.2 | 11.5 | 6 | 52 | 8.7 | 0 | 20 |
| Nov 1 | @ DAL | W 13-12 | 19 | 30 | 210 | 63.3 | 7.0 | 1 | 1 | 22 | 0 | 81.3 | 53.7 | 6 | 32 | 5.3 | 0 | 10 |
| Oct 22 | @ SF | W 20-3 | 18 | 24 | 235 | 75.0 | 9.8 | 1 | 2 | 43 | 5 | 84.5 | 66.0 | 7 | 20 | 2.9 | 0 | 9 |
| Oct 18 | vs CAR | L 27-23 | 18 | 30 | 241 | 60.0 | 8.0 | 1 | 0 | 45 | 4 | 96.7 | 72.4 | 8 | 53 | 6.6 | 0 | 24 |
| Oct 11 | @ CIN | L 27-24 OT | 15 | 23 | 213 | 65.2 | 9.3 | 1 | 1 | 46 | 4 | 91.4 | 44.3 | 3 | 21 | 7.0 | 0 | 9 |
| Oct 5 | vs DET | W 13-10 | 20 | 26 | 287 | 76.9 | 11.0 | 1 | 0 | 50 | 6 | 125.0 | 42.4 | 10 | 40 | 4.0 | 0 | 15 |
| Sep 27 | vs CHI | W 26-0 | 20 | 30 | 235 | 66.7 | 7.8 | 1 | 0 | 30 | 4 | 101.4 | 29.6 | 6 | 28 | 4.7 | 0 | 13 |
| Sep 20 | @ GB | L 27-17 | 19 | 30 | 206 | 63.3 | 6.9 | 2 | 1 | 32 | 2 | 91.8 | 73.5 | 10 | 78 | 7.8 | 0 | 17 |
| Sep 13 | @ STL | L 34-31 OT | 32 | 41 | 251 | 78.0 | 6.1 | 1 | 1 | 23 | 6 | 90.1 | 48.9 | 8 | 31 | 3.9 | 0 | 10 |