| SAN FRANCISCO PASSING | C/ATT | YDS | AVG | TD | INT | SACKS | QBR | RTG |
| Jimmy Garoppolo | 23/32 | 316 | 9.9 | 1 | 2 | 3-26 | 55.1 | 87.5 |
| Deebo Samuel Sr. | 1/1 | 24 | 24.0 | 1 | 0 | 0-0 | 100.0 | 158.3 |
| Team | 24/33 | 314 | 10.3 | 2 | 2 | 3-26 | -- | 100.6 |
| SAN FRANCISCO RUSHING | CAR | YDS | AVG | TD | LONG |
| Elijah Mitchell | 21 | 85 | 4.0 | 0 | 13 |
| Deebo Samuel Sr. | 8 | 45 | 5.6 | 1 | 16 |
| JaMycal Hasty | 1 | 4 | 4.0 | 0 | 4 |
| Jimmy Garoppolo | 1 | 1 | 1.0 | 0 | 1 |
| Team | 31 | 135 | 4.4 | 1 | 16 |
| SAN FRANCISCO RECEIVING | REC | YDS | AVG | TD | LONG | TGTS |
| Brandon Aiyuk | 6 | 107 | 17.8 | 0 | 31 | 7 |
| Deebo Samuel Sr. | 4 | 95 | 23.8 | 0 | 43 | 6 |
| Jauan Jennings | 6 | 94 | 15.7 | 2 | 34 | 7 |
| JaMycal Hasty | 2 | 21 | 10.5 | 0 | 13 | 3 |
| Trent Sherfield | 1 | 13 | 13.0 | 0 | 13 | 1 |
| George Kittle | 5 | 10 | 2.0 | 0 | 6 | 7 |
| Travis Benjamin | 0 | 0 | 0.0 | 0 | 0 | 1 |
| Team | 24 | 340 | 14.2 | 2 | 43 | 32 |
| SAN FRANCISCO FUMBLES | FUM | LOST | REC |
| Jimmy Garoppolo | 1 | 0 | 0 |
| Tom Compton | 0 | 0 | 1 |
| Team | 1 | 0 | 1 |
| SAN FRANCISCO DEFENSE | TOT | SOLO | SACKS | TFL | PD | QB HTS | TD |
| Dre Greenlaw | 12 | 5 | 0 | 0 | 0 | 1 | 0 |
| Dontae Johnson | 9 | 8 | 0 | 0 | 0 | 0 | 0 |
| Fred Warner | 8 | 5 | 0.5 | 1 | 0 | 1 | 0 |
| Arik Armstead | 7 | 4 | 2.5 | 2 | 0 | 3 | 0 |
| Emmanuel Moseley | 6 | 5 | 0 | 0 | 1 | 0 | 0 |
| Jimmie Ward | 6 | 2 | 0 | 0 | 0 | 0 | 0 |
| Nick Bosa | 5 | 2 | 0.5 | 2 | 0 | 3 | 0 |
| Demetrius Flannigan-Fowles | 3 | 1 | 0 | 0 | 0 | 0 | 0 |
| Jaquiski Tartt | 2 | 2 | 0 | 1 | 0 | 0 | 0 |
| Trent Sherfield | 2 | 2 | 0 | 0 | 0 | 0 | 0 |
| D.J. Jones | 2 | 1 | 1 | 1 | 1 | 1 | 0 |
| Kevin Givens | 2 |
| SAN FRANCISCO INTERCEPTIONS | INT | YDS | TD |
| Emmanuel Moseley | 1 | 0 | 0 |
| Ambry Thomas | 1 | 0 | 0 |
| Team | 2 | 0 | 0 |
| SAN FRANCISCO KICK RETURNS | NO | YDS | AVG | LONG | TD |
| JaMycal Hasty | 1 | 11 | 11.0 | 11 | 0 |
| Team | 1 | 11 | 11.0 | 11 | 0 |
| SAN FRANCISCO PUNT RETURNS | NO | YDS | AVG | LONG | TD |
| Travis Benjamin | 1 | 14 | 14.0 | 14 | 0 |
| Team | 1 | 14 | 14.0 | 14 | 0 |
| SAN FRANCISCO KICKING | FG | PCT | LONG | XP | PTS |
| Robbie Gould | 2/2 | 100.0 | 42 | 3/3 | 9 |
| Team | 2/2 | 100.0 | 42 | 3/3 | 9 |
| SAN FRANCISCO PUNTING | NO | YDS | AVG | TB | In 20 | LONG |
| Robbie Gould | 2 | 90 | 45.0 | 0 | 1 | 47 |
| Mitch Wishnowsky | 2 | 85 | 42.5 | 0 | 0 | 43 |
| Team | 4 | 175 | 43.8 | 0 | 1 | 47 |
| LOS ANGELES PASSING | C/ATT | YDS | AVG | TD | INT | SACKS | QBR | RTG |
| Matthew Stafford | 21/32 | 238 | 7.4 | 3 | 2 | 5-37 | 72.6 | 93.0 |
| Team | 21/32 | 201 | 7.4 | 3 | 2 | 5-37 | -- | 93.0 |
| LOS ANGELES RUSHING | CAR | YDS | AVG | TD | LONG |
| Sony Michel | 21 | 43 | 2.0 | 0 | 14 |
| Cooper Kupp | 1 | 18 | 18.0 | 0 | 18 |
| Cam Akers | 5 | 3 | 0.6 | 0 | 2 |
| Team | 27 | 64 | 2.4 | 0 | 18 |
| LOS ANGELES RECEIVING | REC | YDS | AVG | TD | LONG | TGTS |
| Cooper Kupp | 7 | 118 | 16.9 | 1 | 46 | 7 |
| Tyler Higbee | 6 | 55 | 9.2 | 2 | 15 | 8 |
| Van Jefferson | 2 | 31 | 15.5 | 0 |
| 1 |
| 0 |
| 0 |
| 0 |
| 0 |
| 0 |
| Travis Benjamin | 1 | 1 | 0 | 0 | 0 | 0 | 0 |
| Darqueze Dennard | 1 | 1 | 0 | 0 | 0 | 0 | 0 |
| George Kittle | 1 | 1 | 0 | 0 | 0 | 0 | 0 |
| Samson Ebukam | 1 | 1 | 0 | 0 | 0 | 0 | 0 |
| Kentavius Street | 1 | 1 | 0 | 1 | 0 | 1 | 0 |
| Charles Omenihu | 1 | 1 | 0 | 0 | 0 | 0 | 0 |
| Curtis Robinson | 1 | 1 | 0 | 0 | 0 | 0 | 0 |
| Talanoa Hufanga | 1 | 1 | 0 | 0 | 0 | 0 | 0 |
| Arden Key | 1 | 0 | 0.5 | 0 | 0 | 2 | 0 |
| Jordan Willis | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
| Ambry Thomas | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
| Team | 73 | 46 | 5 | 8 | 3 | 13 | 0 |
| 24 |
| 3 |
| Odell Beckham Jr. | 2 | 18 | 9.0 | 0 | 13 | 5 |
| Cam Akers | 3 | 10 | 3.3 | 0 | 6 | 3 |
| Sony Michel | 1 | 6 | 6.0 | 0 | 6 | 4 |
| Ben Skowronek | 0 | 0 | 0.0 | 0 | 0 | 2 |
| Team | 21 | 238 | 11.3 | 3 | 46 | 32 |
| LOS ANGELES FUMBLES | FUM | LOST | REC |
| LOS ANGELES DEFENSE | TOT | SOLO | SACKS | TFL | PD | QB HTS | TD |
| Travin Howard | 8 | 6 | 0 | 0 | 1 | 0 | 0 |
| Taylor Rapp | 8 | 6 | 0 | 0 | 1 | 0 | 0 |
| Troy Reeder | 8 | 4 | 1 | 1 | 1 | 2 | 0 |
| Aaron Donald | 7 | 4 | 0 | 1 | 0 | 1 | 0 |
| Darious Williams | 6 | 4 | 0 | 0 | 0 | 0 | 0 |
| Jordan Fuller | 6 | 3 | 0 | 0 | 0 | 0 | 0 |
| A'Shawn Robinson | 6 | 2 | 1 | 0 | 0 | 1 | 0 |
| Von Miller | 5 | 5 | 1 | 3 | 0 | 2 | 0 |
| Nick Scott | 5 | 3 | 0 | 0 | 1 | 0 | 0 |
| Terrell Burgess | 5 | 2 | 0 | 0 | 0 | 0 | 0 |
| Greg Gaines | 4 | 1 | 0 | 0 | 0 | 0 | 0 |
| Jalen Ramsey | 3 | 3 | 0 | 1 | 1 | 0 | 0 |
| David Long Jr. | 3 | 2 | 0 | 0 | 0 | 0 | 0 |
| Dont'e Deayon | 1 | 1 | 0 | 0 | 0 | 0 | 0 |
| Leonard Floyd | 1 | 1 | 0 | 0 | 0 | 0 | 0 |
| Jake Gervase | 1 | 1 | 0 | 0 | 0 | 0 | 0 |
| Ben Skowronek | 1 | 1 | 0 | 0 | 0 | 0 | 0 |
| Team | 78 | 49 | 3 | 6 | 5 | 6 | 0 |
| LOS ANGELES INTERCEPTIONS | INT | YDS | TD |
| Jalen Ramsey | 1 | 10 | 0 |
| Taylor Rapp | 1 | 0 | 0 |
| Team | 2 | 10 | 0 |
| LOS ANGELES KICK RETURNS | NO | YDS | AVG | LONG | TD |
| Brandon Powell | 2 | 36 | 18.0 | 22 | 0 |
| Team | 2 | 36 | 18.0 | 22 | 0 |
| LOS ANGELES PUNT RETURNS | NO | YDS | AVG | LONG | TD |
| Brandon Powell | 2 | 40 | 20.0 | 31 | 0 |
| Team | 2 | 40 | 20.0 | 31 | 0 |
| LOS ANGELES KICKING | FG | PCT | LONG | XP | PTS |
| Matt Gay | 1/1 | 100.0 | 43 | 3/3 | 6 |
| Team | 1/1 | 100.0 | 43 | 3/3 | 6 |
| LOS ANGELES PUNTING | NO | YDS | AVG | TB | In 20 | LONG |
| Johnny Hekker | 4 | 198 | 49.5 | 0 | 2 | 59 |
| Team | 4 | 198 | 49.5 | 0 | 2 | 59 |