| SAN FRANCISCO PASSING | C/ATT | YDS | AVG | TD | INT | SACKS | QBR | RTG |
| Nick Mullens | 24/38 | 247 | 6.5 | 1 | 2 | 2-15 | 52.9 | 68.6 |
| C.J. Beathard | 0/1 | 0 | 0.0 | 0 | 0 | 0-0 | 6.0 | 39.6 |
| Team | 24/39 | 232 | 6.3 | 1 | 2 | 2-15 | -- | 66.9 |
| SAN FRANCISCO RUSHING | CAR | YDS | AVG | TD | LONG |
| Jerick McKinnon | 18 | 33 | 1.8 | 0 | 9 |
| JaMycal Hasty | 3 | 13 | 4.3 | 0 | 8 |
| Kyle Juszczyk | 1 | 5 | 5.0 | 0 | 5 |
| Nick Mullens | 1 | 3 | 3.0 | 0 | 3 |
| Austin Walter | 1 | 3 | 3.0 | 0 | 3 |
| Brandon Aiyuk | 1 | -8 | -8.0 | 0 | -8 |
| Team | 25 | 49 | 2.0 | 0 | 9 |
| SAN FRANCISCO RECEIVING | REC | YDS | AVG | TD | LONG | TGTS |
| Brandon Aiyuk | 7 | 75 | 10.7 | 1 | 22 | 14 |
| Jordan Reed | 5 | 62 | 12.4 | 0 | 26 | 6 |
| Austin Walter | 1 | 27 | 27.0 | 0 | 27 | 1 |
| Richie James | 3 | 26 | 8.7 | 0 | 14 | 5 |
| Kendrick Bourne | 4 | 26 | 6.5 | 0 | 11 | 5 |
| Ross Dwelley | 1 | 22 | 22.0 | 0 | 22 | 2 |
| Jerick McKinnon | 1 | 13 | 13.0 | 0 | 13 | 3 |
| Kyle Juszczyk | 0 | 0 | 0.0 | 0 | 0 | 1 |
| JaMycal Hasty | 2 | -4 | -2.0 | 0 | 1 | 2 |
| Team | 24 | 247 | 10.3 | 1 | 27 | 39 |
| SAN FRANCISCO FUMBLES | FUM | LOST | REC |
| Richie James | 1 | 1 | 0 |
| Ken Webster | 1 | 1 | 0 |
| Marcell Harris | 0 | 0 | 2 |
| Team | 2 | 2 | 2 |
| SAN FRANCISCO DEFENSE | TOT | SOLO | SACKS | TFL | PD | QB HTS | TD |
| Dre Greenlaw | 11 | 7 | 0 | 0 | 0 | 1 | 0 |
| Tarvarius Moore | 6 | 4 | 0 | 0 | 0 | 0 | 0 |
| Kerry Hyder Jr. | 5 | 2 | 1 | 1 | 0 | 1 | 0 |
| Fred Warner | 5 | 1 | 0 | 0 | 0 | 0 | 0 |
| Jamar Taylor | 4 | 4 | 0 | 0 | 0 | 0 | 0 |
| Jimmie Ward | 4 | 2 | 0 | 0 | 2 | 0 | 0 |
| Jordan Willis | 4 | 1 | 0.5 | 0.5 | 0 | 1 | 0 |
| Dion Jordan | 3 | 2 | 0 | 0 | 0 | 0 | 0 |
| Javon Kinlaw | 3 | 1 | 1.5 | 1.5 | 0 | 3 | 0 |
| Arik Armstead | 2 | 2 | 0 | 0 | 0 | 0 | 0 |
| Ken Webster | 2 | 2 | 0 | 1 | 0 | 0 | 0 |
| Jason Verrett | 2 | 1 | 0 |
| SAN FRANCISCO INTERCEPTIONS | INT | YDS | TD |
| SAN FRANCISCO KICK RETURNS | NO | YDS | AVG | LONG | TD |
| Jerick McKinnon | 1 | 14 | 14.0 | 14 | 0 |
| Team | 1 | 14 | 14.0 | 14 | 0 |
| SAN FRANCISCO PUNT RETURNS | NO | YDS | AVG | LONG | TD |
| Richie James | 1 | 0 | 0.0 | 0 | 0 |
| Ken Webster | 1 | 0 | 0.0 | 0 | 0 |
| Team | 2 | 0 | 0.0 | 0 | 0 |
| SAN FRANCISCO KICKING | FG | PCT | LONG | XP | PTS |
| Robbie Gould | 2/2 | 100.0 | 40 | 1/1 | 7 |
| Team | 2/2 | 100.0 | 40 | 1/1 | 7 |
| SAN FRANCISCO PUNTING | NO | YDS | AVG | TB | In 20 | LONG |
| Mitch Wishnowsky | 5 | 239 | 47.8 | 1 | 0 | 53 |
| Team | 5 | 239 | 47.8 | 1 | 0 | 53 |
| NEW ORLEANS PASSING | C/ATT | YDS | AVG | TD | INT | SACKS | QBR | RTG |
| Drew Brees | 8/13 | 76 | 5.8 | 1 | 0 | 0-0 | 71.0 | 103.4 |
| Jameis Winston | 6/10 | 63 | 6.3 | 0 | 0 | 2-11 | 8.5 | 78.3 |
| Taysom Hill | 0/0 | 0 | 0.0 | 0 | 0 | 1-5 | 2.7 | 0.0 |
| Team | 14/23 | 123 | 6.0 | 1 | 0 | 3-16 | -- | 92.5 |
| NEW ORLEANS RUSHING | CAR | YDS | AVG | TD | LONG |
| Latavius Murray | 9 | 57 | 6.3 | 0 | 18 |
| Taysom Hill | 8 | 45 | 5.6 | 0 | 10 |
| Alvin Kamara | 8 | 15 | 1.9 | 2 | 8 |
| Drew Brees | 1 | -1 | -1.0 | 0 | -1 |
| Jameis Winston | 4 | -2 | -0.5 | 0 | 3 |
| Team | 30 | 114 | 3.8 | 2 | 18 |
| 0 |
| 1 |
| 0 |
| 0 |
| Dontae Johnson | 1 | 1 | 0 | 0 | 0 | 0 | 0 |
| Emmanuel Moseley | 1 | 1 | 0 | 0 | 0 | 0 | 0 |
| Richie James | 1 | 1 | 0 | 0 | 0 | 0 | 0 |
| D.J. Jones | 1 | 1 | 0 | 1 | 0 | 0 | 0 |
| Azeez Al-Shaair | 1 | 1 | 0 | 0 | 0 | 0 | 0 |
| Jared Mayden | 1 | 1 | 0 | 0 | 0 | 0 | 0 |
| Kentavius Street | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
| Team | 58 | 35 | 3 | 5 | 3 | 6 | 0 |
| NEW ORLEANS RECEIVING | REC | YDS | AVG | TD | LONG | TGTS |
| Alvin Kamara | 7 | 83 | 11.9 | 1 | 34 | 8 |
| Michael Thomas | 2 | 27 | 13.5 | 0 | 15 | 7 |
| Deonte Harty | 4 | 24 | 6.0 | 0 | 11 | 4 |
| Emmanuel Sanders | 1 | 5 | 5.0 | 0 | 5 | 1 |
| Jared Cook | 0 | 0 | 0.0 | 0 | 0 | 2 |
| Tre'Quan Smith | 0 | 0 | 0.0 | 0 | 0 | 1 |
| Team | 14 | 139 | 9.9 | 1 | 34 | 23 |
| NEW ORLEANS FUMBLES | FUM | LOST | REC |
| Taysom Hill | 2 | 1 | 0 |
| Deonte Harty | 2 | 1 | 0 |
| Drew Brees | 1 | 0 | 0 |
| Marquez Callaway | 0 | 0 | 2 |
| Team | 5 | 2 | 2 |
| NEW ORLEANS DEFENSE | TOT | SOLO | SACKS | TFL | PD | QB HTS | TD |
| Demario Davis | 12 | 8 | 1 | 3 | 1 | 2 | 0 |
| Marcus Williams | 9 | 4 | 0 | 0.5 | 1 | 0 | 0 |
| C.J. Gardner-Johnson | 8 | 6 | 1 | 2 | 1 | 3 | 0 |
| Marshon Lattimore | 5 | 4 | 0 | 0 | 0 | 0 | 0 |
| David Onyemata | 4 | 4 | 0 | 2 | 1 | 2 | 0 |
| Malcolm Jenkins | 4 | 2 | 0 | 0.5 | 2 | 0 | 0 |
| Kwon Alexander | 4 | 1 | 0 | 0.5 | 0 | 0 | 0 |
| Marcus Davenport | 3 | 3 | 0 | 1 | 0 | 0 | 0 |
| Janoris Jenkins | 3 | 2 | 0 | 0 | 0 | 0 | 0 |
| Cameron Jordan | 3 | 1 | 0 | 0 | 0 | 0 | 0 |
| Malcom Brown | 3 | 1 | 0 | 1.5 | 0 | 0 | 0 |
| P.J. Williams | 2 | 2 | 0 | 0 | 0 | 0 | 0 |
| Shy Tuttle | 2 | 2 | 0 | 0 | 0 | 0 | 0 |
| D.J. Swearinger | 1 | 1 | 0 | 0 | 0 | 0 | 0 |
| Zack Baun | 1 | 1 | 0 | 0 | 0 | 0 | 0 |
| Patrick Robinson | 0 | 0 | 0 | 0 | 2 | 0 | 0 |
| Trey Hendrickson | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
| Team | 64 | 42 | 2 | 11 | 9 | 8 | 0 |
| NEW ORLEANS INTERCEPTIONS | INT | YDS | TD |
| Malcolm Jenkins | 1 | 9 | 0 |
| Patrick Robinson | 1 | 0 | 0 |
| Team | 2 | 9 | 0 |
| NEW ORLEANS KICK RETURNS | NO | YDS | AVG | LONG | TD |
| Deonte Harty | 3 | 122 | 40.7 | 75 | 0 |
| Team | 3 | 122 | 40.7 | 75 | 0 |
| NEW ORLEANS PUNT RETURNS | NO | YDS | AVG | LONG | TD |
| Deonte Harty | 2 | -2 | -1.0 | 0 | 0 |
| Team | 2 | -2 | -1.0 | 0 | 0 |
| NEW ORLEANS KICKING | FG | PCT | LONG | XP | PTS |
| Wil Lutz | 2/2 | 100.0 | 49 | 3/3 | 9 |
| Team | 2/2 | 100.0 | 49 | 3/3 | 9 |
| NEW ORLEANS PUNTING | NO | YDS | AVG | TB | In 20 | LONG |
| Thomas Morstead | 5 | 205 | 41.0 | 0 | 1 | 48 |
| Team | 5 | 205 | 41.0 | 0 | 1 | 48 |