| SAN FRANCISCO PASSING | C/ATT | YDS | AVG | TD | INT | SACKS | QBR | RTG |
| Jimmy Garoppolo | 14/16 | 131 | 8.2 | 2 | 0 | 1-8 | 99.3 | 140.4 |
| Nick Mullens | 8/11 | 71 | 6.5 | 0 | 1 | 2-17 | 1.3 | 51.7 |
| Team | 22/27 | 177 | 7.5 | 2 | 1 | 3-25 | -- | 107.1 |
| SAN FRANCISCO RUSHING | CAR | YDS | AVG | TD | LONG |
| Raheem Mostert | 8 | 92 | 11.5 | 1 | 80 |
| Jerick McKinnon | 3 | 77 | 25.7 | 1 | 55 |
| Tevin Coleman | 14 | 12 | 0.9 | 0 | 6 |
| Jeff Wilson Jr. | 2 | 3 | 1.5 | 0 | 2 |
| Nick Mullens | 2 | -2 | -1.0 | 0 | 0 |
| Team | 29 | 182 | 6.3 | 2 | 80 |
| SAN FRANCISCO RECEIVING | REC | YDS | AVG | TD | LONG | TGTS |
| Kendrick Bourne | 4 | 67 | 16.8 | 0 | 24 | 5 |
| Jordan Reed | 7 | 50 | 7.1 | 2 | 18 | 8 |
| Tevin Coleman | 2 | 28 | 14.0 | 0 | 18 | 2 |
| Brandon Aiyuk | 2 | 21 | 10.5 | 0 | 13 | 3 |
| Raheem Mostert | 2 | 15 | 7.5 | 0 | 10 | 2 |
| Trent Taylor | 2 | 10 | 5.0 | 0 | 9 | 3 |
| Kyle Juszczyk | 2 | 6 | 3.0 | 0 | 4 | 2 |
| Ross Dwelley | 1 | 5 | 5.0 | 0 | 5 | 1 |
| Jerick McKinnon | 0 | 0 | 0.0 | 0 | 0 | 1 |
| Team | 22 | 202 | 9.2 | 2 | 24 | 27 |
| SAN FRANCISCO FUMBLES | FUM | LOST | REC |
| Nick Mullens | 2 | 0 | 0 |
| Team | 2 | 0 | 0 |
| SAN FRANCISCO DEFENSE | TOT | SOLO | SACKS | TFL | PD | QB HTS | TD |
| Fred Warner | 12 | 9 | 0 | 0 | 0 | 0 | 0 |
| Kerry Hyder Jr. | 9 | 3 | 0 | 1 | 0 | 2 | 0 |
| Jimmie Ward | 7 | 4 | 0 | 0 | 0 | 0 | 0 |
| Jaquiski Tartt | 5 | 4 | 0 | 0 | 0 | 0 | 0 |
| Kwon Alexander | 5 | 3 | 0 | 1 | 0 | 0 | 0 |
| Ahkello Witherspoon | 5 | 3 | 0 | 0 | 0 | 0 | 0 |
| D.J. Jones | 3 | 3 | 0 | 1 | 0 | 0 | 0 |
| Arik Armstead | 3 | 1 | 1 | 1 | 1 | 3 | 0 |
| Tarvarius Moore | 2 | 2 | 0 | 0 | 0 | 0 | 0 |
| Emmanuel Moseley | 2 | 1 | 0 | 0 | 2 | 0 | 0 |
| Azeez Al-Shaair | 2 | 1 | 0 | 0 | 0 | 0 | 0 |
| Javon Kinlaw | 2 |
| SAN FRANCISCO INTERCEPTIONS | INT | YDS | TD |
| SAN FRANCISCO KICK RETURNS | NO | YDS | AVG | LONG | TD |
| Jerick McKinnon | 3 | 71 | 23.7 | 29 | 0 |
| Team | 3 | 71 | 23.7 | 29 | 0 |
| SAN FRANCISCO PUNT RETURNS | NO | YDS | AVG | LONG | TD |
| SAN FRANCISCO KICKING | FG | PCT | LONG | XP | PTS |
| Robbie Gould | 1/1 | 100.0 | 46 | 4/4 | 7 |
| Team | 1/1 | 100.0 | 46 | 4/4 | 7 |
| SAN FRANCISCO PUNTING | NO | YDS | AVG | TB | In 20 | LONG |
| Mitch Wishnowsky | 4 | 199 | 49.8 | 1 | 2 | 59 |
| Team | 4 | 199 | 49.8 | 1 | 2 | 59 |
| NEW YORK PASSING | C/ATT | YDS | AVG | TD | INT | SACKS | QBR | RTG |
| Sam Darnold | 21/32 | 179 | 5.6 | 1 | 0 | 1-6 | 72.3 | 90.5 |
| Team | 21/32 | 173 | 5.6 | 1 | 0 | 1-6 | -- | 90.5 |
| NEW YORK RUSHING | CAR | YDS | AVG | TD | LONG |
| Frank Gore | 21 | 63 | 3.0 | 0 | 13 |
| La'Mical Perine | 3 | 17 | 5.7 | 0 | 10 |
| Josh Malone | 1 | 12 | 12.0 | 0 | 12 |
| Sam Darnold | 2 | 7 | 3.5 | 0 | 8 |
| Kalen Ballage | 1 | 5 | 5.0 | 0 | 5 |
| Josh Adams | 1 | 0 | 0.0 | 0 | 0 |
| Team | 29 | 104 | 3.6 | 0 | 13 |
| NEW YORK RECEIVING | REC | YDS | AVG | TD | LONG | TGTS |
| Chris Hogan |
| 1 |
| 0 |
| 0 |
| 0 |
| 0 |
| 0 |
| Solomon Thomas | 2 | 0 | 0 | 0 | 0 | 0 | 0 |
| Trent Williams | 1 | 1 | 0 | 0 | 0 | 0 | 0 |
| Dontae Johnson | 1 | 1 | 0 | 0 | 0 | 0 | 0 |
| K'Waun Williams | 1 | 1 | 0 | 0 | 1 | 0 | 0 |
| Marcell Harris | 1 | 1 | 0 | 0 | 0 | 0 | 0 |
| Dre Greenlaw | 1 | 1 | 0 | 0 | 0 | 0 | 0 |
| Kevin Givens | 1 | 1 | 0 | 0 | 0 | 1 | 0 |
| Mitch Wishnowsky | 1 | 1 | 0 | 0 | 0 | 0 | 0 |
| Team | 66 | 42 | 1 | 4 | 4 | 6 | 0 |
| 6 |
| 75 |
| 12.5 |
| 0 |
| 27 |
| 8 |
| Braxton Berrios | 6 | 59 | 9.8 | 1 | 30 | 8 |
| Josh Malone | 4 | 16 | 4.0 | 0 | 13 | 6 |
| Breshad Perriman | 2 | 12 | 6.0 | 0 | 9 | 2 |
| Kalen Ballage | 2 | 12 | 6.0 | 0 | 8 | 2 |
| Chris Herndon | 1 | 5 | 5.0 | 0 | 5 | 4 |
| Frank Gore | 0 | 0 | 0.0 | 0 | 0 | 2 |
| Team | 21 | 179 | 8.5 | 1 | 30 | 32 |
| NEW YORK FUMBLES | FUM | LOST | REC |
| NEW YORK DEFENSE | TOT | SOLO | SACKS | TFL | PD | QB HTS | TD |
| Quinnen Williams | 7 | 4 | 2 | 4 | 0 | 2 | 0 |
| Marcus Maye | 7 | 3 | 0 | 0.5 | 1 | 0 | 0 |
| Brian Poole | 6 | 6 | 0 | 1 | 1 | 0 | 0 |
| Neville Hewitt | 6 | 6 | 0 | 0 | 0 | 1 | 0 |
| Bradley McDougald | 5 | 4 | 0 | 0 | 0 | 0 | 0 |
| Jordan Jenkins | 4 | 2 | 1 | 1.5 | 0 | 2 | 0 |
| Steve McLendon | 4 | 2 | 0 | 0 | 0 | 0 | 0 |
| Avery Williamson | 3 | 2 | 0 | 0 | 0 | 0 | 0 |
| Kyle Phillips | 3 | 2 | 0 | 0 | 0 | 1 | 0 |
| Alec Ogletree | 2 | 2 | 0 | 2 | 0 | 0 | 0 |
| Pierre Desir | 2 | 2 | 0 | 0 | 1 | 0 | 0 |
| Bless Austin | 2 | 2 | 0 | 0 | 0 | 1 | 0 |
| Harvey Langi | 1 | 1 | 0 | 0 | 0 | 0 | 0 |
| Tarell Basham | 1 | 1 | 0 | 0 | 0 | 2 | 0 |
| Quincy Wilson | 1 | 1 | 0 | 1 | 0 | 0 | 0 |
| Josh Adams | 1 | 1 | 0 | 0 | 0 | 0 | 0 |
| Folorunso Fatukasi | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
| John Franklin-Myers | 1 | 0 | 0 | 0 | 0 | 3 | 0 |
| Frankie Luvu | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
| Arthur Maulet | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
| Team | 59 | 41 | 3 | 10 | 3 | 12 | 0 |
| NEW YORK INTERCEPTIONS | INT | YDS | TD |
| Pierre Desir | 1 | 23 | 0 |
| Team | 1 | 23 | 0 |
| NEW YORK KICK RETURNS | NO | YDS | AVG | LONG | TD |
| Josh Malone | 2 | 49 | 24.5 | 32 | 0 |
| Ashtyn Davis | 1 | 27 | 27.0 | 27 | 0 |
| Team | 3 | 76 | 25.3 | 32 | 0 |
| NEW YORK PUNT RETURNS | NO | YDS | AVG | LONG | TD |
| NEW YORK KICKING | FG | PCT | LONG | XP | PTS |
| Sam Ficken | 2/2 | 100.0 | 41 | 1/1 | 7 |
| Team | 2/2 | 100.0 | 41 | 1/1 | 7 |
| NEW YORK PUNTING | NO | YDS | AVG | TB | In 20 | LONG |
| Braden Mann | 5 | 222 | 44.4 | 1 | 1 | 52 |
| Team | 5 | 222 | 44.4 | 1 | 1 | 52 |