| LOS ANGELES PASSING | C/ATT | YDS | AVG | TD | INT | SACKS | QBR | RTG |
| Jared Goff | 22/28 | 292 | 10.4 | 3 | 0 | 0-0 | 93.0 | 145.8 |
| Team | 22/28 | 292 | 10.4 | 3 | 0 | 0-0 | -- | 145.8 |
| LOS ANGELES RUSHING | CAR | YDS | AVG | TD | LONG |
| Todd Gurley | 28 | 113 | 4.0 | 2 | 29 |
| Tavon Austin | 3 | 14 | 4.7 | 0 | 8 |
| Jared Goff | 1 | -1 | -1.0 | 0 | -1 |
| Team | 32 | 126 | 3.9 | 2 | 29 |
| LOS ANGELES RECEIVING | REC | YDS | AVG | TD | LONG | TGTS |
| Robert Woods | 6 | 108 | 18.0 | 0 | 31 | 7 |
| Sammy Watkins | 6 | 106 | 17.7 | 2 | 47 | 7 |
| Todd Gurley | 5 | 36 | 7.2 | 1 | 27 | 7 |
| Derek Carrier | 1 | 17 | 17.0 | 0 | 17 | 1 |
| Cooper Kupp | 2 | 17 | 8.5 | 0 | 13 | 2 |
| Tyler Higbee | 1 | 4 | 4.0 | 0 | 4 | 3 |
| Pharoh Cooper | 1 | 4 | 4.0 | 0 | 4 | 1 |
| Team | 22 | 292 | 13.3 | 3 | 47 | 28 |
| LOS ANGELES FUMBLES | FUM | LOST | REC |
| Tavon Austin | 1 | 1 | 0 |
| Pharoh Cooper | 1 | 1 | 0 |
| Todd Gurley | 1 | 0 | 0 |
| Nickell Robey-Coleman | 0 | 0 | 1 |
| Team | 3 | 2 | 1 |
| LOS ANGELES DEFENSE | TOT | SOLO | SACKS | TFL | PD | QB HTS | TD |
| Alec Ogletree | 9 | 7 | 0 | 0 | 1 | 1 | 0 |
| Mark Barron | 7 | 6 | 0 | 0 | 0 | 0 | 0 |
| Maurice Alexander | 7 | 5 | 0 | 0 | 0 | 1 | 0 |
| Michael Brockers | 6 | 6 | 0 | 2 | 0 | 0 | 0 |
| Trumaine Johnson | 6 | 5 | 0 | 0 | 1 | 0 | 0 |
| Cody Davis | 6 | 5 | 0 | 0 | 0 | 0 | 0 |
| Connor Barwin | 5 | 3 | 1 | 1 | 0 | 1 | 0 |
| Nickell Robey-Coleman | 5 | 2 | 0 | 0 | 2 | 0 | 0 |
| Aaron Donald | 3 | 2 | 1 | 1 | 0 | 2 | 0 |
| Matt Longacre | 3 | 2 | 1 | 1 | 0 | 1 | 0 |
| Tanzel Smart | 3 | 1 | 0 | 0 | 0 | 0 | 0 |
| Blake Countess | 2 | 2 | 0 | 0 |
| LOS ANGELES INTERCEPTIONS | INT | YDS | TD |
| Nickell Robey-Coleman | 1 | 25 | 0 |
| Team | 1 | 25 | 0 |
| LOS ANGELES KICK RETURNS | NO | YDS | AVG | LONG | TD |
| Pharoh Cooper | 3 | 83 | 27.7 | 28 | 0 |
| Team | 3 | 83 | 27.7 | 28 | 0 |
| LOS ANGELES PUNT RETURNS | NO | YDS | AVG | LONG | TD |
| Tavon Austin | 1 | 0 | 0.0 | 0 | 0 |
| Team | 1 | 0 | 0.0 | 0 | 0 |
| LOS ANGELES KICKING | FG | PCT | LONG | XP | PTS |
| Greg Zuerlein | 2/2 | 100.0 | 48 | 5/5 | 11 |
| Team | 2/2 | 100.0 | 48 | 5/5 | 11 |
| LOS ANGELES PUNTING | NO | YDS | AVG | TB | In 20 | LONG |
| Johnny Hekker | 2 | 113 | 56.5 | 0 | 0 | 64 |
| Team | 2 | 113 | 56.5 | 0 | 0 | 64 |
| SAN FRANCISCO PASSING | C/ATT | YDS | AVG | TD | INT | SACKS | QBR | RTG |
| Brian Hoyer | 23/37 | 332 | 9.0 | 2 | 1 | 4-24 | 72.7 | 98.0 |
| Team | 23/37 | 308 | 9.0 | 2 | 1 | 4-24 | -- | 98.0 |
| SAN FRANCISCO RUSHING | CAR | YDS | AVG | TD | LONG |
| Carlos Hyde | 25 | 84 | 3.4 | 2 | 20 |
| Raheem Mostert | 4 | 11 | 2.8 | 0 | 7 |
| Brian Hoyer | 1 | 9 | 9.0 | 1 | 9 |
| Matt Breida | 3 | 9 | 3.0 | 0 | 10 |
| Team | 33 | 113 | 3.4 | 3 | 20 |
| SAN FRANCISCO RECEIVING | REC | YDS | AVG | TD | LONG | TGTS |
| Pierre Garcon | 7 | 142 | 20.3 | 0 | 59 | 10 |
| Marquise Goodwin | 2 | 62 | 31.0 |
| 0 |
| 0 |
| 0 |
| Tyrunn Walker | 2 | 1 | 0 | 0 | 0 | 0 | 0 |
| Lamarcus Joyner | 2 | 1 | 0 | 0 | 0 | 0 | 0 |
| John Johnson III | 2 | 1 | 0 | 0 | 0 | 0 | 0 |
| Morgan Fox | 1 | 1 | 1 | 1 | 0 | 1 | 0 |
| Tavon Austin | 1 | 1 | 0 | 0 | 0 | 0 | 0 |
| Ethan Westbrooks | 1 | 1 | 0 | 0 | 0 | 0 | 0 |
| Troy Hill | 1 | 1 | 0 | 0 | 1 | 0 | 0 |
| Tyler Higbee | 1 | 1 | 0 | 0 | 0 | 0 | 0 |
| Cory Littleton | 1 | 1 | 0 | 0 | 0 | 0 | 0 |
| Robert Quinn | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
| Team | 75 | 55 | 4 | 6 | 5 | 7 | 0 |
| 0 |
| 50 |
| 5 |
| Kyle Juszczyk | 1 | 34 | 34.0 | 0 | 34 | 1 |
| Trent Taylor | 3 | 32 | 10.7 | 1 | 18 | 4 |
| Aldrick Robinson | 2 | 23 | 11.5 | 0 | 17 | 4 |
| Matt Breida | 3 | 20 | 6.7 | 0 | 12 | 4 |
| Carlos Hyde | 3 | 10 | 3.3 | 0 | 5 | 4 |
| George Kittle | 1 | 8 | 8.0 | 0 | 8 | 3 |
| Garrett Celek | 1 | 1 | 1.0 | 1 | 1 | 2 |
| Team | 23 | 332 | 14.4 | 2 | 59 | 37 |
| SAN FRANCISCO FUMBLES | FUM | LOST | REC |
| Raheem Mostert | 1 | 1 | 0 |
| Aldrick Robinson | 0 | 0 | 1 |
| Kyle Nelson | 0 | 0 | 1 |
| Team | 1 | 1 | 2 |
| SAN FRANCISCO DEFENSE | TOT | SOLO | SACKS | TFL | PD | QB HTS | TD |
| Jimmie Ward | 7 | 7 | 0 | 1 | 0 | 0 | 0 |
| K'Waun Williams | 7 | 6 | 0 | 0 | 0 | 0 | 0 |
| Jaquiski Tartt | 7 | 6 | 0 | 1 | 1 | 0 | 0 |
| Ray-Ray Armstrong | 6 | 4 | 0 | 1 | 0 | 0 | 0 |
| Rashard Robinson | 6 | 4 | 0 | 0 | 0 | 0 | 0 |
| DeForest Buckner | 5 | 5 | 0 | 0 | 0 | 1 | 0 |
| NaVorro Bowman | 4 | 3 | 0 | 0 | 0 | 0 | 0 |
| Earl Mitchell | 4 | 3 | 0 | 0.5 | 0 | 0 | 0 |
| Dontae Johnson | 3 | 2 | 0 | 0 | 0 | 0 | 0 |
| Garrett Celek | 2 | 2 | 0 | 0 | 0 | 0 | 0 |
| Tank Carradine | 2 | 2 | 0 | 0 | 0 | 1 | 0 |
| Eli Harold | 2 | 2 | 0 | 1 | 0 | 0 | 0 |
| Dekoda Watson | 1 | 1 | 0 | 0 | 0 | 0 | 0 |
| Brock Coyle | 1 | 1 | 0 | 0 | 0 | 0 | 0 |
| Raheem Mostert | 1 | 1 | 0 | 0 | 0 | 0 | 0 |
| Arik Armstead | 1 | 1 | 0 | 0 | 0 | 0 | 0 |
| Victor Bolden | 1 | 1 | 0 | 0 | 0 | 0 | 0 |
| Solomon Thomas | 1 | 1 | 0 | 0 | 0 | 0 | 0 |
| Lorenzo Jerome | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
| Team | 61 | 52 | 0 | 4.5 | 1 | 3 | 0 |
| SAN FRANCISCO INTERCEPTIONS | INT | YDS | TD |
| SAN FRANCISCO KICK RETURNS | NO | YDS | AVG | LONG | TD |
| Victor Bolden | 2 | 36 | 18.0 | 18 | 0 |
| Raheem Mostert | 1 | 20 | 20.0 | 20 | 0 |
| Team | 3 | 56 | 18.7 | 20 | 0 |
| SAN FRANCISCO PUNT RETURNS | NO | YDS | AVG | LONG | TD |
| Trent Taylor | 1 | 9 | 9.0 | 9 | 0 |
| Victor Bolden | 1 | 0 | 0.0 | 0 | 0 |
| Team | 2 | 9 | 4.5 | 9 | 0 |
| SAN FRANCISCO KICKING | FG | PCT | LONG | XP | PTS |
| Robbie Gould | 2/2 | 100.0 | 48 | 3/4 | 9 |
| Team | 2/2 | 100.0 | 48 | 3/4 | 9 |
| SAN FRANCISCO PUNTING | NO | YDS | AVG | TB | In 20 | LONG |
| Bradley Pinion | 2 | 83 | 41.5 | 0 | 2 | 51 |
| Team | 2 | 83 | 41.5 | 0 | 2 | 51 |