NFL scores · Lucas Oil Stadium
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SF33017023
IND33107326
San Francisco 49ers
| SAN FRANCISCO PASSING | C/ATT | YDS | AVG | TD | INT | SACKS | QBR | RTG |
| Brian Hoyer | 29/46 | 353 | 7.7 | 2 | 0 | 2-17 | 57.4 | 101.1 |
| Team | 29/46 | 336 | 7.7 | 2 | 0 | 2-17 | -- | 101.1 |
| SAN FRANCISCO RUSHING | CAR | YDS | AVG | TD | LONG |
| Matt Breida | 10 | 49 | 4.9 | 0 | 14 |
| Carlos Hyde | 8 | 11 | 1.4 | 0 | 6 |
| Kyle Juszczyk | 1 | 3 | 3.0 | 0 | 3 |
| Raheem Mostert | 1 | 3 | 3.0 | 0 | 3 |
| Brian Hoyer | 2 | 0 | 0.0 | 0 | 0 |
| Team | 22 | 66 | 3.0 | 0 | 14 |
| SAN FRANCISCO RECEIVING | REC | YDS | AVG | TD | LONG | TGTS |
| Marquise Goodwin | 5 | 116 | 23.2 | 0 | 51 | 11 |
| Pierre Garcon | 8 | 94 | 11.8 | 0 | 25 | 11 |
| George Kittle | 7 | 83 | 11.9 | 1 | 27 | 9 |
| Matt Breida | 3 | 22 | 7.3 | 0 | 10 | 5 |
| Kyle Juszczyk | 2 | 14 | 7.0 | 1 | 8 | 4 |
| Carlos Hyde | 1 | 7 | 7.0 | 0 | 7 | 1 |
| Garrett Celek | 1 | 6 | 6.0 | 0 | 6 | 1 |
| Trent Taylor | 1 | 6 | 6.0 | 0 | 6 | 2 |
| Aldrick Robinson | 1 | 5 | 5.0 | 0 | 5 | 1 |
| Team | 29 | 353 | 12.2 | 2 | 51 | 45 |
| SAN FRANCISCO FUMBLES | FUM | LOST | REC |
| Brian Hoyer | 2 | 0 | 0 |
| Team | 2 | 0 | 0 |
| SAN FRANCISCO DEFENSE | TOT | SOLO | SACKS | TFL | PD | QB HTS | TD |
| NaVorro Bowman | 10 | 5 | 0 | 0 | 0 | 0 | 0 |
| Dontae Johnson | 9 | 8 | 0 | 1 | 0 | 0 | 0 |
| Ray-Ray Armstrong | 7 | 6 | 0 | 0 | 1 | 0 | 0 |
| Jaquiski Tartt | 7 | 3 | 0.5 | 0.5 | 0 | 1 | 0 |
| Arik Armstead | 5 | 1 | 0.5 | 1 | 1 | 1 | 0 |
| DeForest Buckner | 5 | 1 | 0.5 | 2.5 | 0 | 2 | 0 |
| Jimmie Ward | 4 | 3 | 0 | 0 | 0 | 0 | 0 |
| K'Waun Williams | 4 | 3 | 0 | 1 | 0 | 0 | 0 |
| Brock Coyle | 3 | 2 | 0.5 | 0.5 | 0 | 1 | 0 |
| Elvis Dumervil | 3 | 1 | 1.5 | 1.5 | 0 | 2 | 0 |
| Rashard Robinson | 3 | 1 | 0 | 0.5 | 2 | 0 | 0 |
| Earl Mitchell | 2 | 2 |
| SAN FRANCISCO INTERCEPTIONS | INT | YDS | TD |
| Ray-Ray Armstrong | 1 | 29 | 0 |
| Team | 1 | 29 | 0 |
| SAN FRANCISCO KICK RETURNS | NO | YDS | AVG | LONG | TD |
| Victor Bolden | 4 | 59 | 14.8 | 28 | 0 |
| Team | 4 | 59 | 14.8 | 28 | 0 |
| SAN FRANCISCO PUNT RETURNS | NO | YDS | AVG | LONG | TD |
| Trent Taylor | 1 | 0 | 0.0 | 0 | 0 |
| Team | 1 | 0 | 0.0 | 0 | 0 |
| SAN FRANCISCO KICKING | FG | PCT | LONG | XP | PTS |
| Robbie Gould | 3/3 | 100.0 | 43 | 2/2 | 11 |
| Team | 3/3 | 100.0 | 43 | 2/2 | 11 |
| SAN FRANCISCO PUNTING | NO | YDS | AVG | TB | In 20 | LONG |
| Bradley Pinion | 6 | 274 | 45.7 | 0 | 1 | 55 |
| Team | 6 | 274 | 45.7 | 0 | 1 | 55 |
Indianapolis Colts
| INDIANAPOLIS PASSING | C/ATT | YDS | AVG | TD | INT | SACKS | QBR | RTG |
| Jacoby Brissett | 22/34 | 314 | 9.2 | 0 | 1 | 4-26 | 38.6 | 82.2 |
| Team | 22/34 | 288 | 9.2 | 0 | 1 | 4-26 | -- | 82.2 |
| INDIANAPOLIS RUSHING | CAR | YDS | AVG | TD | LONG |
| Marlon Mack | 9 | 91 | 10.1 | 1 | 35 |
| Frank Gore | 14 | 48 | 3.4 | 0 | 16 |
| Jacoby Brissett | 8 | 14 | 1.8 | 1 | 5 |
| Robert Turbin | 4 | 6 | 1.5 | 0 | 4 |
| Team | 35 | 159 | 4.5 | 2 | 35 |
| INDIANAPOLIS RECEIVING | REC | YDS | AVG | TD | LONG | TGTS |
| T.Y. Hilton | 7 | 177 | 25.3 | 0 | 63 | 9 |
| Frank Gore | 3 | 38 | 12.7 | 0 |