| CLEVELAND PASSING | C/ATT | YDS | AVG | TD | INT | SACKS | QBR | RTG |
| Brady Quinn | 14/36 | 185 | 5.1 | 0 | 0 | 1-9 | 42.5 | 55.9 |
| Team | 14/36 | 176 | 5.1 | 0 | 0 | 1-9 | -- | 55.9 |
| CLEVELAND RUSHING | CAR | YDS | AVG | TD | LONG |
| Jerome Harrison | 3 | 80 | 26.7 | 1 | 72 |
| Jamal Lewis | 18 | 65 | 3.6 | 0 | 16 |
| Brady Quinn | 4 | 18 | 4.5 | 0 | 12 |
| Joshua Cribbs | 1 | 2 | 2.0 | 1 | 2 |
| Donte' Stallworth | 1 | -4 | -4.0 | 0 | -4 |
| Team | 27 | 161 | 6.0 | 2 | 72 |
| CLEVELAND RECEIVING | REC | YDS | AVG | TD | LONG | TGTS |
| Braylon Edwards | 8 | 104 | 13.0 | 0 | 23 | 0 |
| Kellen Winslow | 3 | 40 | 13.3 | 0 | 16 | 0 |
| Jerome Harrison | 1 | 21 | 21.0 | 0 | 21 | 0 |
| Charles Ali | 1 | 12 | 12.0 | 0 | 12 | 0 |
| Syndric Steptoe | 1 | 8 | 8.0 | 0 | 8 | 0 |
| Team | 14 | 185 | 13.2 | 0 | 23 | 0 |
| CLEVELAND FUMBLES | FUM | LOST | REC |
| Ahtyba Rubin | 0 | 0 | 1 |
| Team | 0 | 0 | 1 |
| CLEVELAND DEFENSE | TOT | SOLO | SACKS | TFL | PD | QB HTS | TD |
| D'Qwell Jackson | 11 | 5 | 0 | 0 | 1 | 0 | 0 |
| Andra Davis | 9 | 5 | 0 | 0 | 1 | 0 | 0 |
| Eric Wright | 6 | 6 | 0 | 0 | 0 | 0 | 0 |
| Shaun Rogers | 6 | 5 | 0 | 0 | 1 | 0 | 0 |
| Shaun Smith | 6 | 5 | 0 | 0 | 0 | 0 | 0 |
| Willie McGinest | 5 | 4 | 0 | 0 | 0 | 0 | 0 |
| Kamerion Wimbley | 5 | 4 | 0 | 0 | 1 | 0 | 0 |
| Mike Adams | 5 | 2 | 0 | 0 | 0 | 0 | 0 |
| Corey Williams | 4 | 2 | 0 | 0 | 0 | 0 | 0 |
| Brandon McDonald | 4 | 1 | 0 | 0 | 1 | 0 | 0 |
| Terry Cousin | 3 | 2 | 0 | 0 | 0 | 0 | 0 |
| Brodney Pool | 2 | 2 | 0 | 0 | 1 | 0 | 0 |
| CLEVELAND INTERCEPTIONS | INT | YDS | TD |
| Andra Davis | 1 | 4 | 0 |
| Brandon McDonald | 1 | 3 | 0 |
| Kamerion Wimbley | 1 | 2 | 0 |
| Team | 3 | 9 | 0 |
| CLEVELAND KICK RETURNS | NO | YDS | AVG | LONG | TD |
| Joshua Cribbs | 3 | 64 | 21.3 | 26 | 0 |
| Team | 3 | 64 | 21.3 | 26 | 0 |
| CLEVELAND PUNT RETURNS | NO | YDS | AVG | LONG | TD |
| CLEVELAND KICKING | FG | PCT | LONG | XP | PTS |
| Phil Dawson | 5/5 | 100.0 | 56 | 2/2 | 17 |
| Team | 5/5 | 100.0 | 56 | 2/2 | 17 |
| CLEVELAND PUNTING | NO | YDS | AVG | TB | In 20 | LONG |
| Dave Zastudil | 5 | 230 | 46.0 | 0 | 2 | 65 |
| Team | 5 | 230 | 46.0 | 0 | 2 | 65 |
| BUFFALO PASSING | C/ATT | YDS | AVG | TD | INT | SACKS | QBR | RTG |
| Trent Edwards | 16/26 | 148 | 5.7 | 1 | 3 | 0-0 | 4.5 | 50.3 |
| Team | 16/26 | 148 | 5.7 | 1 | 3 | 0-0 | -- | 50.3 |
| BUFFALO RUSHING | CAR | YDS | AVG | TD | LONG |
| Marshawn Lynch | 23 | 119 | 5.2 | 0 | 28 |
| Fred Jackson | 12 | 60 | 5.0 | 0 | 19 |
| Trent Edwards | 3 | 7 | 2.3 | 1 | 4 |
| Team | 38 | 186 | 4.9 | 1 | 28 |
| BUFFALO RECEIVING | REC | YDS | AVG | TD | LONG | TGTS |
| Marshawn Lynch | 10 | 58 | 5.8 | 1 | 18 | 0 |
| Stevie Johnson | 3 | 41 | 13.7 | 0 | 21 | 0 |
| Robert Royal | 1 | 22 | 22.0 | 0 | 22 | 0 |
| Kris Griffin | 2 | 2 | 0 | 0 | 0 | 0 | 0 |
| Ahtyba Rubin | 2 | 2 | 0 | 0 | 0 | 0 | 0 |
| Alex Hall | 2 | 2 | 0 | 0 | 0 | 0 | 0 |
| Sean Jones | 2 | 1 | 0 | 0 | 0 | 0 | 0 |
| Travis Daniels | 2 | 1 | 0 | 0 | 0 | 0 | 0 |
| Nick Sorensen | 1 | 1 | 0 | 0 | 0 | 0 | 0 |
| Shantee Orr | 1 | 1 | 0 | 0 | 0 | 0 | 0 |
| Joshua Cribbs | 1 | 1 | 0 | 0 | 0 | 0 | 0 |
| Leon Williams | 1 | 1 | 0 | 0 | 0 | 0 | 0 |
| Santonio Thomas | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
| Team | 80 | 55 | 0 | 0 | 7 | 0 | 0 |
| 1 |
| 21 |
| 21.0 |
| 0 |
| 21 |
| 0 |
| Derek Fine | 1 | 6 | 6.0 | 0 | 6 | 0 |
| Team | 16 | 148 | 9.3 | 1 | 22 | 0 |
| BUFFALO FUMBLES | FUM | LOST | REC |
| Fred Jackson | 2 | 1 | 0 |
| Team | 2 | 1 | 0 |
| BUFFALO DEFENSE | TOT | SOLO | SACKS | TFL | PD | QB HTS | TD |
| Keith Ellison | 8 | 4 | 0 | 0 | 0 | 0 | 0 |
| Terrence McGee | 6 | 6 | 0 | 0 | 6 | 0 | 0 |
| Paul Posluszny | 6 | 4 | 0 | 0 | 0 | 0 | 0 |
| Kyle Williams | 5 | 3 | 0 | 0 | 0 | 0 | 0 |
| Kawika Mitchell | 5 | 2 | 1 | 0 | 0 | 0 | 0 |
| Marcus Stroud | 5 | 2 | 0 | 0 | 2 | 0 | 0 |
| Bryan Scott | 4 | 4 | 0 | 0 | 2 | 0 | 0 |
| Ko Simpson | 4 | 4 | 0 | 0 | 1 | 0 | 0 |
| Donte Whitner | 3 | 0 | 0 | 0 | 0 | 0 | 0 |
| Jabari Greer | 2 | 2 | 0 | 0 | 0 | 0 | 0 |
| Ryan Denney | 1 | 1 | 0 | 0 | 0 | 0 | 0 |
| Corey McIntyre | 1 | 1 | 0 | 0 | 0 | 0 | 0 |
| Lee Evans | 1 | 1 | 0 | 0 | 0 | 0 | 0 |
| Teddy Lehman | 1 | 1 | 0 | 0 | 0 | 0 | 0 |
| George Wilson | 1 | 1 | 0 | 0 | 0 | 0 | 0 |
| Copeland Bryan | 1 | 1 | 0 | 0 | 0 | 0 | 0 |
| Leodis McKelvin | 1 | 1 | 0 | 0 | 1 | 0 | 0 |
| Derek Fine | 1 | 1 | 0 | 0 | 0 | 0 | 0 |
| Stevie Johnson | 1 | 1 | 0 | 0 | 0 | 0 | 0 |
| Spencer Johnson | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
| Team | 57 | 40 | 1 | 0 | 13 | 0 | 1 |
| BUFFALO INTERCEPTIONS | INT | YDS | TD |
| BUFFALO KICK RETURNS | NO | YDS | AVG | LONG | TD |
| Leodis McKelvin | 3 | 185 | 61.7 | 98 | 1 |
| Fred Jackson | 4 | 61 | 15.3 | 19 | 0 |
| Team | 7 | 246 | 35.1 | 98 | 1 |
| BUFFALO PUNT RETURNS | NO | YDS | AVG | LONG | TD |
| Roscoe Parrish | 1 | 34 | 34.0 | 34 | 0 |
| Fred Jackson | 1 | 0 | 0.0 | 0 | 0 |
| Team | 2 | 34 | 17.0 | 34 | 0 |
| BUFFALO KICKING | FG | PCT | LONG | XP | PTS |
| Rian Lindell | 2/3 | 66.7 | 31 | 3/3 | 9 |
| Team | 2/3 | 66.7 | 31 | 3/3 | 9 |
| BUFFALO PUNTING | NO | YDS | AVG | TB | In 20 | LONG |
| Brian Moorman | 3 | 108 | 36.0 | 0 | 2 | 40 |
| Team | 3 | 108 | 36.0 | 0 | 2 | 40 |