Brandon McCarthy · Roost| Aug 21 | @ CIN | L 10-7 | 2.1 | 8 | 7 | 7 | 1 | 1 | 2 | 7 | 6 | 62 | 16 | 14.0 | L(2-8) | - | 5.44 |
| Aug 16 | @ PIT | L 6-2 | 5.2 | 7 | 4 | 4 | 0 | 3 | 5 | 10 | 8 | 100 | 26 | 41.0 | L(2-7) | - | 4.84 |
| Aug 10 | vs NYM | L 4-1 | 7.0 | 6 | 2 | 2 | 1 | 1 | 4 | 10 | 11 | 97 | 27 | 60.0 | L(2-6) | - | 4.73 |
| Aug 4 | @ BOS | L 4-0 | 4.1 | 5 | 2 | 2 | 0 | 3 | 5 | 6 | 7 | 97 | 22 | 47.0 | L(2-5) | - | 4.94 |
| May 30 | @ TEX | L 9-5 | 2.2 | 9 | 6 | 6 | 1 | 0 | 0 | 6 | 11 | 55 | 17 | 16.0 | L(2-4) | - | 5.00 |
| May 24 | vs SD | W 5-2 | 7.0 | 5 | 1 | 1 | 0 | 2 | 2 | 13 | 10 | 96 | 27 | 63.0 | W(2-3) | - | 4.36 |
| May 18 | @ MIA | W 1-0 | 9.0 | 3 | 0 | 0 | 0 | 2 | 5 | 9 | 15 | 99 | 31 | 84.0 | W(1-3) | - | 4.74 |
| May 12 | vs PHI | L 4-2 F/10 | 8.0 | 7 | 0 | 0 | 0 | 0 | 5 | 12 | 12 | 88 | 29 | 73.0 | - | - | 5.63 |
| May 7 | @ LAD | W 5-3 | 6.1 | 8 | 3 | 3 | 1 | 1 | 3 | 12 | 11 | 101 | 27 | 47.0 | - | - | 6.75 |
| May 1 | vs SF | L 9-6 | 6.0 | 8 | 4 | 4 | 2 | 1 | 6 | 5 | 15 | 91 | 27 | 45.0 | - | - | 7.22 |
| Apr 26 | vs COL | L 6-3 | 6.0 | 9 | 6 | 6 | 1 | 0 | 7 | 9 | 11 | 105 | 27 | 37.0 | L(0-3) | - | 7.48 |
| Apr 21 | @ COL | W 5-4 | 6.0 | 8 | 4 | 4 | 1 | 0 | 2 | 8 | 15 | 96 | 25 | 42.0 | - | - | 7.06 |
| Apr 16 | @ NYY | L 4-2 | 4.0 | 9 | 3 | 3 | 1 | 2 | 4 | 7 | 10 | 102 | 23 | 34.0 | L(0-2) | - | 7.47 |
| Apr 9 | vs PIT | L 6-5 | 6.2 | 10 | 6 | 4 | 0 | 2 | 4 | 13 | 13 | 115 | 32 | 36.0 | L(0-1) | - | 7.71 |
| Apr 3 | vs STL | W 10-9 F/16 | 5.0 | 9 | 6 | 6 | 0 | 0 | 1 | 15 | 8 | 73 | 25 | 26.0 | - | - | 10.80 |