Brandon McCarthy · Roost| Jul 20 | vs CLE | L 3-2 | 5.2 | 6 | 3 | 3 | 1 | 3 | 4 | 8 | 9 | 100 | 24 | 46.0 | L(4-7) | - | 5.53 |
| Jul 15 | @ LAA | W 5-4 F/11 | 6.0 | 6 | 4 | 3 | 0 | 2 | 4 | 11 | 10 | 95 | 27 | 48.0 | - | - | 5.59 |
| Jul 7 | vs BAL | L 3-0 | 6.0 | 4 | 2 | 1 | 1 | 2 | 3 | 9 | 10 | 97 | 24 | 59.0 | L(4-6) | - | 5.70 |
| Jul 2 | @ BOS | L 7-3 | 3.2 | 6 | 4 | 4 | 0 | 3 | 1 | 6 | 9 | 81 | 19 | 31.0 | L(4-5) | - | 6.17 |
| Jun 9 | vs MIL | W 4-3 | 5.0 | 4 | 1 | 1 | 0 | 0 | 5 | 3 | 11 | 78 | 19 | 60.0 | - | - | 5.90 |
| May 25 | vs BOS | L 10-6 | 2.0 | 1 | 4 | 4 | 0 | 4 | 1 | 1 | 5 | 66 | 11 | 35.0 | - | - | 6.35 |
| May 20 | @ HOU | W 14-1 | 6.0 | 4 | 1 | 1 | 0 | 2 | 2 | 8 | 12 | 100 | 24 | 60.0 | W(4-4) | - | 5.82 |
| May 15 | @ TB | L 4-3 F/10 | 6.0 | 6 | 3 | 3 | 0 | 3 | 7 | 8 | 8 | 110 | 26 | 52.0 | - | - | 6.51 |
| May 10 | @ NYY | W 14-2 | 5.1 | 5 | 1 | 1 | 1 | 2 | 3 | 1 | 16 | 104 | 22 | 55.0 | W(3-4) | - | 6.89 |
| May 4 | vs TOR | W 7-1 | 6.0 | 2 | 1 | 1 | 1 | 4 | 1 | 7 | 12 | 94 | 24 | 61.0 | W(2-4) | - | 7.96 |
| Apr 29 | @ TOR | L 7-3 | 3.0 | 6 | 5 | 5 | 0 | 4 | 4 | 4 | 7 | 86 | 20 | 27.0 | L(1-4) | - | 9.90 |
| Apr 25 | @ CLE | L 8-7 F/11 | 2.0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 5 | 34 | 7 | 0.0 | - | - | 9.00 |
| Apr 20 | vs OAK | L 16-4 | 1.0 | 4 | 6 | 6 | 0 | 2 | 1 | 0 | 6 | 43 | 10 | 20.0 | L(1-3) | - | 10.20 |
| Apr 15 | @ SEA | L 14-6 | 2.0 | 6 | 6 | 6 | 3 | 1 | 1 | 5 | 7 | 56 | 14 | 20.0 | L(1-2) | - | 7.07 |
| Apr 9 | vs TB | W 8-4 | 6.0 | 5 | 2 | 2 | 0 | 2 | 5 | 5 | 12 | 98 | 24 | 57.0 | W(1-1) | - | 3.75 |
| Apr 4 | @ LAA | L 5-3 | 6.0 | 10 | 5 | 3 | 0 | 1 | 0 | 16 | 11 | 79 | 29 | 35.0 | L(0-1) | - | 4.50 |
