Dan Haren · Roost| Aug 25 | @ DET | L 5-3 | 5.2 | 8 | 2 | 2 | 0 | 0 | 7 | 7 | 10 | 95 | 24 | 52.0 | - | - | 4.82 |
| Aug 16 | vs TB | L 7-0 | 3.2 | 7 | 5 | 5 | 2 | 0 | 2 | 5 | 11 | 61 | 18 | 29.0 | L(8-10) | - | 4.90 |
| Aug 11 | vs SEA | L 7-4 | 3.1 | 5 | 7 | 5 | 1 | 3 | 0 | 6 | 10 | 63 | 19 | 23.0 | L(8-9) | - | 4.68 |
| Aug 5 | @ CHW | L 4-2 | 6.0 | 4 | 1 | 1 | 1 | 2 | 4 | 4 | 14 | 112 | 24 | 62.0 | - | - | 4.44 |
| Jul 27 | vs TB | W 3-1 | 6.0 | 5 | 1 | 1 | 1 | 1 | 6 | 7 | 10 | 97 | 24 | 63.0 | W(8-8) | - | 4.59 |
| Jul 22 | vs TEX | W 7-4 | 6.0 | 3 | 2 | 2 | 1 | 3 | 3 | 12 | 6 | 95 | 25 | 58.0 | W(7-8) | - | 4.76 |
| Jul 3 | @ CLE | L 9-5 | 4.1 | 9 | 7 | 6 | 1 | 1 | 1 | 6 | 14 | 69 | 22 | 19.0 | L(6-8) | - | 4.86 |
| Jun 28 | @ TOR | W 9-7 | 6.0 | 7 | 6 | 6 | 2 | 1 | 3 | 9 | 13 | 91 | 26 | 36.0 | W(6-7) | - | 4.53 |
| Jun 22 | vs LAD | W 8-5 | 5.0 | 9 | 5 | 5 | 1 | 3 | 5 | 7 | 11 | 102 | 26 | 31.0 | W(5-7) | - | 4.24 |
| Jun 15 | vs ARI | L 5-0 | 6.1 | 8 | 5 | 5 | 1 | 2 | 5 | 10 | 11 | 107 | 28 | 40.0 | L(4-7) | - | 3.97 |
| Jun 9 | @ COL | W 11-5 | 5.1 | 10 | 4 | 4 | 4 | 1 | 4 | 7 | 15 | 107 | 27 | 35.0 | W(4-6) | - | 3.73 |
| Jun 3 | vs TEX | L 7-3 | 5.0 | 7 | 2 | 2 | 0 | 2 | 2 | 6 | 14 | 104 | 24 | 45.0 | L(3-6) | - | 3.52 |
| May 29 | vs NYY | W 5-1 | 7.0 | 8 | 1 | 1 | 0 | 0 | 7 | 11 | 12 | 102 | 30 | 64.0 | W(3-5) | - | 3.52 |
| May 24 | @ SEA | W 3-0 | 9.0 | 4 | 0 | 0 | 0 | 0 | 14 | 8 | 9 | 126 | 31 | 93.0 | W(2-5) | - | 3.76 |
| May 19 | @ SD | L 3-2 | 6.2 | 6 | 3 | 3 | 0 | 1 | 5 | 13 | 8 | 85 | 27 | 54.0 | L(1-5) | - | 4.37 |
| May 14 | vs OAK | L 5-0 | 6.0 | 6 | 4 | 4 | 1 | 4 | 5 | 9 | 9 | 106 | 28 | 45.0 | L(1-4) | - | 4.41 |
| May 8 | @ MIN | L 5-0 | 3.2 | 8 | 5 | 5 | 1 | 2 | 0 | 7 | 11 | 78 | 20 | 23.0 | L(1-3) | - | 4.19 |
| May 3 | vs TOR | L 5-0 | 7.0 | 5 | 5 | 3 | 1 | 2 | 5 | 8 | 12 | 101 | 27 | 54.0 | L(1-2) | - | 3.43 |
| Apr 28 | @ CLE | W 2-1 | 8.0 | 4 | 1 | 1 | 0 | 2 | 7 | 7 | 14 | 119 | 30 | 75.0 | W(1-1) | - | 3.34 |
| Apr 22 | vs BAL | L 3-2 F/10 | 7.1 | 6 | 2 | 2 | 0 | 1 | 9 | 9 | 8 | 115 | 27 | 66.0 | - | - | 4.07 |
| Apr 17 | vs OAK | L 5-3 | 6.2 | 5 | 1 | 1 | 1 | 0 | 2 | 12 | 10 | 85 | 24 | 62.0 | - | - | 4.76 |
| Apr 12 | @ MIN | L 10-9 | 5.0 | 9 | 3 | 3 | 1 | 1 | 7 | 4 | 13 | 94 | 25 | 43.0 | - | - | 6.97 |
| Apr 7 | vs KC | L 6-3 | 5.1 | 11 | 5 | 5 | 2 | 1 | 5 | 7 | 14 | 93 | 27 | 30.0 | L(0-1) | - | 8.44 |