Jon Garland · Roost| Aug 19 | @ SEA | L 11-5 | 2.2 | 10 | 10 | 5 | 2 | 1 | 1 | 7 | 11 | 77 | 20 | 8.0 | L(8-9) | - | 4.84 |
| Aug 14 | @ OAK | L 4-3 | 5.2 | 6 | 4 | 4 | 3 | 3 | 3 | 5 | 14 | 100 | 25 | 41.0 | L(8-8) | - | 4.63 |
| Aug 8 | vs CLE | W 6-4 F/13 | 7.0 | 6 | 3 | 3 | 1 | 0 | 5 | 4 | 18 | 101 | 28 | 58.0 | - | - | 4.56 |
| Aug 2 | @ NYY | W 13-9 | 1.1 | 9 | 8 | 8 | 1 | 0 | 1 | 5 | 7 | 56 | 13 | 5.0 | - | - | 4.60 |
| Jul 27 | vs TOR | W 4-3 | 7.1 | 10 | 3 | 3 | 0 | 1 | 3 | 4 | 24 | 114 | 32 | 48.0 | W(8-7) | - | 4.12 |
| Jul 22 | @ BOS | L 8-5 | 4.2 | 6 | 6 | 6 | 2 | 5 | 3 | 5 | 12 | 112 | 25 | 26.0 | L(7-7) | - | 4.15 |
| Jul 17 | @ CLE | L 6-5 F/11 | 6.0 | 7 | 3 | 3 | 0 | 3 | 2 | 7 | 14 | 122 | 26 | 45.0 | - | - | 3.88 |
| Jul 12 | @ BAL | W 9-7 | 7.0 | 8 | 2 | 2 | 0 | 2 | 3 | 9 | 15 | 97 | 29 | 54.0 | W(7-6) | - | 3.85 |
| Jul 6 | vs MIN | L 20-14 | 3.1 | 11 | 12 | 11 | 2 | 3 | 0 | 11 | 11 | 90 | 25 | -11.0 | L(6-6) | - | 3.92 |
| Jul 1 | @ KC | W 3-1 F/7 | 7.0 | 7 | 1 | 0 | 0 | 1 | 4 | 13 | 11 | 107 | 29 | 64.0 | W(6-5) | - | 3.15 |
| Jun 26 | @ TB | W 6-1 | 7.0 | 5 | 1 | 1 | 1 | 2 | 3 | 9 | 14 | 110 | 29 | 64.0 | W(5-5) | - | 3.36 |
| Jun 20 | vs FLA | L 5-4 | 7.0 | 3 | 3 | 2 | 0 | 1 | 6 | 6 | 13 | 109 | 26 | 66.0 | L(4-5) | - | 3.51 |
| Jun 15 | @ PIT | L 4-2 | 6.0 | 11 | 4 | 4 | 0 | 0 | 4 | 15 | 9 | 96 | 28 | 38.0 | L(4-4) | - | 3.59 |
| Jun 9 | vs HOU | L 3-2 | 7.0 | 8 | 1 | 1 | 1 | 1 | 4 | 8 | 15 | 116 | 28 | 60.0 | - | - | 3.42 |
| Jun 4 | vs NYY | W 6-4 | 8.1 | 7 | 2 | 1 | 0 | 3 | 3 | 12 | 15 | 119 | 33 | 63.0 | W(4-3) | - | 3.61 |
| May 30 | @ MIN | L 7-6 | 6.0 | 5 | 6 | 6 | 0 | 5 | 2 | 10 | 10 | 103 | 27 | 35.0 | - | - | 3.91 |
| May 23 | vs OAK | L 4-0 | 6.1 | 10 | 4 | 4 | 1 | 1 | 4 | 9 | 14 | 114 | 28 | 40.0 | L(3-3) | - | 3.43 |
| May 17 | vs NYY | W 4-1 | 7.0 | 6 | 1 | 1 | 0 | 4 | 2 | 10 | 12 | 100 | 28 | 59.0 | W(3-2) | - | 3.18 |
| May 11 | vs KC | W 2-1 | 8.1 | 4 | 1 | 1 | 0 | 1 | 3 | 15 | 10 | 101 | 29 | 73.0 | W(2-2) | - | 3.44 |
| May 5 | @ LAA | W 6-3 | 7.0 | 8 | 3 | 3 | 0 | 1 | 1 | 11 | 16 | 83 | 29 | 49.0 | W(1-2) | - | 3.92 |
| Apr 28 | vs LAA | L 3-0 | 7.0 | 5 | 3 | 3 | 1 | 1 | 0 | 13 | 12 | 102 | 26 | 54.0 | L(0-2) | - | 3.93 |
| Apr 22 | @ DET | L 6-5 F/12 | 8.0 | 5 | 3 | 2 | 0 | 1 | 3 | 12 | 13 | 105 | 29 | 64.0 | - | - | 3.95 |
| Apr 17 | vs TEX | L 8-1 | 7.0 | 5 | 5 | 5 | 2 | 1 | 3 | 4 | 19 | 96 | 27 | 49.0 | L(0-1) | - | 4.66 |
| Apr 10 | @ OAK | L 2-1 | 7.0 | 3 | 0 | 0 | 0 | 3 | 3 | 9 | 11 | 113 | 26 | 71.0 | - | - | 3.65 |
| Apr 4 | vs CLE | L 8-7 | 5.1 | 7 | 5 | 5 | 1 | 4 | 5 | 5 | 13 | 105 | 27 | 35.0 | - | - | 8.44 |