Jose Berrios · Roost| Aug 23 | vs DET | L 9-6 | 5.1 | 10 | 5 | 5 | 1 | 2 | 5 | 6 | 13 | 93 | 26 | 31.0 | L(10-7) | - | 3.53 |
| Aug 17 | @ TEX | W 12-7 | 4.1 | 7 | 7 | 3 | 2 | 3 | 6 | 7 | 8 | 92 | 24 | 32.0 | - | - | 3.37 |
| Aug 11 | vs CLE | L 7-3 F/10 | 6.0 | 6 | 3 | 3 | 1 | 1 | 4 | 7 | 13 | 96 | 25 | 51.0 | - | - | 3.29 |
| Aug 6 | vs ATL | L 12-7 | 5.2 | 9 | 9 | 9 | 2 | 4 | 7 | 7 | 11 | 97 | 29 | 18.0 | L(10-6) | - | 3.24 |
| Jul 31 | @ MIA | W 7-4 | 7.0 | 2 | 0 | 0 | 0 | 0 | 11 | 6 | 6 | 81 | 23 | 84.0 | W(10-5) | - | 2.80 |
| Jul 25 | @ CHW | W 10-3 | 7.0 | 6 | 3 | 2 | 1 | 1 | 8 | 11 | 9 | 106 | 29 | 62.0 | W(9-5) | - | 2.94 |
| Jul 20 | vs OAK | L 5-4 | 5.2 | 5 | 0 | 0 | 0 | 3 | 4 | 11 | 6 | 113 | 26 | 60.0 | - | - | 2.96 |
| Jul 14 | @ CLE | L 4-3 | 5.0 | 6 | 3 | 3 | 0 | 3 | 6 | 6 | 9 | 92 | 24 | 46.0 | - | - | 3.10 |
| Jul 9 | vs NL | W 4-3 | 1.0 | 1 | 0 | 0 | 0 | 0 | 2 | 0 | 1 | 13 | 4 | 0.0 | - | HLD(1) | 0.00 |
| Jul 4 | @ OAK | L 7-2 | 5.0 | 6 | 3 | 3 | 1 | 3 | 2 | 7 | 11 | 92 | 24 | 42.0 | L(8-5) | - | 3.00 |
| Jun 28 | @ CHW | L 6-4 | 7.1 | 9 | 6 | 3 | 2 | 0 | 5 | 12 | 16 | 105 | 33 | 47.0 | L(8-4) | - | 2.89 |
| Jun 22 | @ KC | W 5-3 F/10 | 7.0 | 5 | 2 | 2 | 0 | 3 | 3 | 9 | 12 | 90 | 27 | 59.0 | - | - | 2.84 |
| Jun 17 | vs BOS | L 2-0 | 8.0 | 5 | 1 | 1 | 0 | 0 | 10 | 6 | 12 | 109 | 28 | 78.0 | L(8-3) | - | 2.86 |
| Jun 12 | vs SEA | L 9-6 F/10 | 6.2 | 7 | 1 | 1 | 1 | 2 | 6 | 8 | 12 | 107 | 28 | 60.0 | - | - | 3.01 |
| Jun 6 | @ CLE | W 5-4 | 6.0 | 2 | 2 | 1 | 1 | 1 | 6 | 10 | 6 | 107 | 23 | 67.0 | W(8-2) | - | 3.14 |
| May 31 | @ TB | W 5-3 | 6.2 | 3 | 3 | 3 | 1 | 3 | 8 | 9 | 6 | 99 | 27 | 61.0 | - | - | 3.27 |
| May 24 | vs CHW | W 11-4 | 6.2 | 9 | 4 | 1 | 0 | 0 | 4 | 13 | 12 | 98 | 31 | 50.0 | W(7-2) | - | 3.20 |
| May 18 | @ SEA | W 18-4 | 4.2 | 8 | 4 | 4 | 0 | 0 | 6 | 5 | 11 | 105 | 22 | 38.0 | - | - | 3.39 |
| May 13 | vs LAA | L 5-4 | 5.2 | 12 | 5 | 5 | 2 | 3 | 3 | 15 | 9 | 101 | 30 | 25.0 | L(6-2) | - | 3.05 |
| May 7 | @ TOR | W 3-0 | 7.0 | 4 | 0 | 0 | 0 | 0 | 5 | 6 | 14 | 92 | 25 | 74.0 | W(6-1) | - | 2.53 |
| May 2 | vs HOU | W 8-2 | 7.0 | 7 | 2 | 2 | 1 | 0 | 5 | 6 | 17 | 88 | 28 | 60.0 | W(5-1) | - | 2.91 |
| Apr 27 | vs BAL | W 9-2 | 6.0 | 7 | 2 | 2 | 0 | 0 | 8 | 3 | 14 | 101 | 25 | 58.0 | W(4-1) | - | 2.97 |
| Apr 20 | @ BAL | W 6-5 | 6.0 | 8 | 4 | 4 | 3 | 3 | 5 | 4 | 7 | 104 | 28 | 42.0 | W(3-1) | - | 2.97 |
| Apr 14 | vs DET | W 6-4 | 6.2 | 4 | 2 | 2 | 1 | 1 | 7 | 9 | 8 | 98 | 26 | 64.0 | W(2-1) | - | 2.30 |
| Apr 7 | @ PHI | L 2-1 | 6.0 | 2 | 2 | 2 | 1 | 3 | 7 | 7 | 6 | 98 | 23 | 64.0 | L(1-1) | - | 2.18 |
| Apr 2 | @ KC | W 5-4 F/10 | 7.0 | 7 | 3 | 3 | 1 | 0 | 4 | 9 | 14 | 86 | 27 | 55.0 | - | - | 1.84 |
| Mar 28 | vs CLE | W 2-0 | 7.2 | 2 | 0 | 0 | 0 | 1 | 10 | 5 | 10 | 96 | 26 | 84.0 | W(1-0) | - | 0.00 |