Jose Quintana · Roost| Aug 31 | @ CIN | W 5-3 F/13 | 4.2 | 7 | 2 | 2 | 0 | 1 | 1 | 12 | 6 | 78 | 20 | 42.0 | - | - | 3.47 |
| Aug 26 | vs ATL | L 11-4 | 5.0 | 7 | 4 | 2 | 0 | 2 | 3 | 8 | 9 | 86 | 22 | 42.0 | L(4-6) | - | 3.45 |
| Aug 21 | @ ARI | W 6-4 | 2.2 | 7 | 4 | 2 | 0 | 3 | 0 | 6 | 7 | 73 | 17 | 29.0 | - | - | 3.45 |
| Aug 16 | vs COL | W 5-4 | 5.0 | 4 | 2 | 2 | 0 | 2 | 3 | 8 | 8 | 75 | 21 | 52.0 | - | - | 3.38 |
| Aug 10 | @ COL | W 9-5 | 6.0 | 7 | 2 | 2 | 0 | 2 | 6 | 8 | 10 | 103 | 26 | 54.0 | W(4-5) | - | 3.37 |
| Aug 4 | vs CHC | W 7-2 | 6.0 | 1 | 1 | 1 | 1 | 2 | 7 | 6 | 5 | 86 | 20 | 71.0 | - | - | 3.39 |
| Jul 29 | vs PHI | L 4-2 F/10 | 5.2 | 4 | 0 | 0 | 0 | 2 | 4 | 6 | 10 | 83 | 22 | 63.0 | - | - | 3.50 |
| Jul 23 | vs MIA | W 1-0 | 7.0 | 4 | 0 | 0 | 0 | 0 | 4 | 11 | 8 | 81 | 24 | 73.0 | W(3-5) | - | 3.70 |
| Jul 15 | @ COL | L 13-2 | 5.0 | 7 | 6 | 6 | 0 | 2 | 3 | 11 | 7 | 103 | 23 | 30.0 | L(2-5) | - | 3.99 |
| Jul 10 | @ MIL | W 8-6 | 4.1 | 6 | 4 | 4 | 0 | 2 | 4 | 6 | 9 | 80 | 21 | 37.0 | - | - | 3.59 |
| Jul 5 | vs NYY | W 5-2 | 5.0 | 6 | 1 | 1 | 0 | 0 | 7 | 8 | 6 | 96 | 21 | 58.0 | W(2-4) | - | 3.33 |
| Jun 28 | @ WSH | L 3-1 | 6.0 | 4 | 1 | 1 | 0 | 2 | 6 | 4 | 13 | 97 | 25 | 64.0 | - | - | 3.43 |
| Jun 23 | vs CHC | W 8-7 F/10 | 6.0 | 6 | 2 | 2 | 0 | 1 | 6 | 9 | 7 | 83 | 23 | 57.0 | - | - | 3.60 |
| Jun 18 | vs SF | L 7-5 | 5.1 | 5 | 3 | 3 | 2 | 2 | 5 | 6 | 10 | 95 | 23 | 49.0 | - | - | 3.66 |
| Jun 12 | @ ATL | L 5-3 | 5.0 | 6 | 4 | 4 | 3 | 1 | 4 | 6 | 11 | 92 | 22 | 42.0 | L(1-4) | - | 3.53 |
| Jun 7 | vs DET | L 5-3 | 3.1 | 7 | 4 | 4 | 0 | 1 | 5 | 5 | 7 | 74 | 18 | 34.0 | L(1-3) | - | 3.19 |
| Jun 1 | @ LAD | W 8-4 | 4.1 | 7 | 2 | 2 | 0 | 1 | 3 | 6 | 10 | 84 | 20 | 43.0 | - | - | 2.68 |
| May 27 | @ SD | L 4-3 | 5.1 | 5 | 2 | 2 | 0 | 2 | 4 | 8 | 7 | 96 | 21 | 52.0 | - | - | 2.54 |
| May 21 | vs STL | L 5-4 | 3.2 | 7 | 5 | 2 | 0 | 1 | 4 | 6 | 9 | 77 | 20 | 36.0 | L(1-2) | - | 2.43 |
| May 15 | vs CIN | W 1-0 | 7.0 | 3 | 0 | 0 | 0 | 1 | 5 | 10 | 8 | 89 | 24 | 75.0 | - | - | 2.19 |
| May 9 | vs LAD | W 5-1 | 6.0 | 2 | 0 | 0 | 0 | 4 | 5 | 6 | 9 | 102 | 25 | 69.0 | W(1-1) | - | 2.70 |
| May 4 | @ DET | W 7-2 | 5.0 | 4 | 2 | 2 | 0 | 1 | 3 | 11 | 3 | 77 | 22 | 53.0 | - | - | 3.38 |
| Apr 28 | vs MIL | L 3-2 | 5.0 | 4 | 1 | 1 | 1 | 0 | 9 | 3 | 7 | 78 | 19 | 64.0 | - | - | 3.32 |
| Apr 22 | @ CHC | W 4-2 | 4.2 | 3 | 2 | 2 | 0 | 3 | 3 | 6 | 7 | 87 | 19 | 50.0 | - | - | 3.86 |
| Apr 17 | vs WSH | W 5-3 | 4.0 | 5 | 3 | 3 | 0 | 3 | 2 | 6 | 9 | 85 | 20 | 39.0 | - | - | 3.86 |
| Apr 12 | vs CHC | L 2-1 | 5.1 | 5 | 1 | 1 | 1 | 2 | 3 | 8 | 7 | 71 | 20 | 55.0 | L(0-1) | - | 1.69 |
