Jose Quintana · Roost| Aug 13 | @ SF | L 7-1 | 6.2 | 4 | 4 | 4 | 0 | 2 | 7 | 6 | 8 | 90 | 27 | 55.0 | L(0-1) | - | - |
| Aug 8 | @ SEA | L 4-1 | 5.2 | 7 | 4 | 2 | 1 | 2 | 4 | 6 | 15 | 93 | 27 | 45.0 | L(6-8) | - | 3.04 |
| Aug 3 | vs MIN | L 16-3 | 5.0 | 5 | 1 | 0 | 0 | 2 | 5 | 6 | 9 | 115 | 23 | 58.0 | - | - | 3.04 |
| Jul 29 | @ DET | W 11-4 | 6.0 | 9 | 2 | 2 | 0 | 2 | 2 | 9 | 14 | 101 | 27 | 46.0 | W(6-7) | - | 3.15 |
| Jul 23 | vs KC | L 2-1 | 7.0 | 7 | 1 | 1 | 0 | 2 | 3 | 16 | 6 | 112 | 27 | 60.0 | - | - | 3.15 |
| Jul 18 | vs HOU | W 3-2 | 5.0 | 3 | 2 | 2 | 0 | 2 | 8 | 5 | 5 | 106 | 20 | 59.0 | - | - | 3.26 |
| Jul 10 | @ BOS | L 4-3 F/10 | 7.0 | 2 | 3 | 3 | 0 | 2 | 7 | 5 | 11 | 111 | 25 | 66.0 | - | - | 3.24 |
| Jul 5 | vs SEA | L 3-2 F/14 | 7.2 | 4 | 0 | 0 | 0 | 1 | 10 | 12 | 5 | 109 | 28 | 80.0 | - | - | 3.20 |
| Jun 29 | @ TOR | W 4-0 | 7.0 | 3 | 0 | 0 | 0 | 2 | 7 | 9 | 7 | 114 | 25 | 76.0 | W(5-7) | - | 3.44 |
| Jun 24 | @ BAL | W 4-2 | 7.0 | 6 | 1 | 1 | 1 | 3 | 8 | 9 | 8 | 115 | 28 | 66.0 | W(4-7) | - | 3.69 |
| Jun 19 | @ MIN | L 4-2 | 7.0 | 6 | 2 | 2 | 1 | 1 | 6 | 6 | 14 | 108 | 27 | 62.0 | - | - | 3.87 |
| Jun 13 | vs KC | L 7-2 | 6.0 | 8 | 6 | 6 | 0 | 1 | 6 | 6 | 14 | 110 | 27 | 37.0 | L(3-7) | - | 3.98 |
| Jun 8 | @ LAA | L 4-2 | 4.1 | 7 | 4 | 4 | 0 | 4 | 4 | 8 | 8 | 96 | 24 | 33.0 | L(3-6) | - | 3.59 |
| Jun 2 | @ LAD | L 5-2 | 6.0 | 6 | 5 | 0 | 0 | 2 | 5 | 14 | 6 | 105 | 27 | 53.0 | L(3-5) | - | 3.31 |
| May 26 | vs CLE | W 6-2 | 6.0 | 5 | 2 | 2 | 0 | 2 | 5 | 10 | 7 | 107 | 24 | 57.0 | W(3-4) | - | 3.61 |
| May 21 | @ KC | L 3-1 | 7.1 | 8 | 3 | 3 | 0 | 1 | 4 | 16 | 9 | 111 | 30 | 53.0 | L(2-4) | - | 3.67 |
| May 16 | @ HOU | W 7-2 | 5.0 | 7 | 2 | 2 | 0 | 2 | 5 | 9 | 8 | 102 | 24 | 48.0 | W(2-3) | - | 3.67 |
| May 10 | vs ARI | L 4-3 | 6.0 | 7 | 3 | 3 | 0 | 1 | 5 | 5 | 15 | 109 | 26 | 50.0 | L(1-3) | - | 3.67 |
| May 5 | @ CHC | W 3-1 F/12 | 7.0 | 1 | 1 | 1 | 0 | 3 | 3 | 12 | 7 | 95 | 25 | 71.0 | - | - | 3.56 |
| Apr 29 | vs DET | L 4-3 | 6.0 | 8 | 3 | 3 | 0 | 0 | 10 | 6 | 9 | 107 | 25 | 54.0 | - | - | 4.00 |
| Apr 24 | @ DET | L 7-4 | 6.0 | 7 | 3 | 3 | 1 | 0 | 3 | 8 | 13 | 98 | 24 | 49.0 | L(1-2) | - | 3.90 |
| Apr 19 | @ TEX | L 6-3 | 5.0 | 9 | 5 | 5 | 1 | 2 | 1 | 8 | 12 | 98 | 23 | 28.0 | L(1-1) | - | 3.75 |
| Apr 13 | vs CLE | W 4-3 | 6.0 | 5 | 1 | 1 | 1 | 2 | 6 | 8 | 9 | 121 | 25 | 62.0 | - | - | 2.37 |
| Apr 8 | @ COL | W 15-3 | 7.0 | 5 | 2 | 2 | 1 | 2 | 4 | 12 | 8 | 86 | 26 | 61.0 | W(1-0) | - | 2.77 |
| Apr 3 | vs MIN | L 10-9 | 6.0 | 5 | 5 | 2 | 0 | 3 | 8 | 8 | 8 | 109 | 27 | 53.0 | - | - | 3.00 |
