Shelby Miller · Roost| Aug 16 | vs SD | L 9-5 | 6.0 | 4 | 4 | 4 | 0 | 6 | 5 | 8 | 8 | 110 | 27 | 47.0 | - | - | 4.25 |
| Aug 11 | @ MIA | L 6-5 | 5.0 | 8 | 5 | 5 | 2 | 2 | 5 | 8 | 9 | 92 | 24 | 34.0 | L(8-9) | - | 4.17 |
| Aug 6 | vs BOS | L 2-1 | 7.0 | 4 | 1 | 1 | 0 | 1 | 4 | 8 | 12 | 88 | 25 | 68.0 | - | - | 3.99 |
| Jul 31 | @ SD | W 6-2 | 6.0 | 3 | 2 | 2 | 2 | 0 | 5 | 8 | 8 | 85 | 21 | 63.0 | W(8-8) | - | 4.14 |
| Jul 26 | @ CHC | W 6-3 | 5.2 | 3 | 2 | 2 | 1 | 0 | 3 | 9 | 8 | 87 | 20 | 58.0 | - | - | 4.20 |
| Jul 20 | vs LAD | L 4-3 | 1.0 | 2 | 0 | 0 | 0 | 1 | 0 | 2 | 2 | 17 | 5 | 0.0 | - | - | 4.25 |
| Jul 10 | vs PIT | L 9-1 | 5.0 | 5 | 4 | 4 | 0 | 4 | 1 | 3 | 16 | 92 | 24 | 38.0 | L(7-8) | - | 4.29 |
| Jul 5 | vs MIA | L 6-5 | 5.1 | 9 | 3 | 3 | 0 | 1 | 2 | 10 | 12 | 107 | 26 | 39.0 | - | - | 4.15 |
| Jun 29 | @ LAD | L 6-0 | 5.0 | 7 | 6 | 6 | 1 | 3 | 4 | 5 | 11 | 71 | 24 | 30.0 | L(7-7) | - | 4.10 |
| Jun 24 | @ COL | L 10-5 | 2.2 | 6 | 3 | 3 | 0 | 5 | 2 | 6 | 5 | 73 | 18 | 31.0 | - | - | 3.75 |
| Jun 19 | vs PHI | L 4-1 | 6.2 | 7 | 4 | 4 | 1 | 3 | 4 | 8 | 14 | 93 | 29 | 45.0 | L(7-6) | - | 3.56 |
| Jun 14 | vs WSH | W 4-1 | 6.2 | 4 | 1 | 1 | 0 | 4 | 7 | 8 | 8 | 101 | 27 | 65.0 | - | - | 3.42 |
| Jun 7 | @ TOR | W 5-0 | 9.0 | 3 | 0 | 0 | 0 | 1 | 5 | 9 | 16 | 105 | 31 | 85.0 | W(7-5) | - | 3.59 |
| Jun 2 | vs KC | L 6-0 | 7.0 | 7 | 4 | 4 | 1 | 1 | 2 | 13 | 12 | 95 | 29 | 48.0 | L(6-5) | - | 4.06 |
| May 28 | vs NYY | L 7-4 | 5.0 | 9 | 7 | 7 | 0 | 2 | 1 | 8 | 14 | 87 | 26 | 20.0 | L(6-4) | - | 3.94 |
| May 23 | @ CIN | L 5-3 | 5.0 | 5 | 4 | 4 | 1 | 1 | 5 | 5 | 10 | 80 | 21 | 45.0 | L(6-3) | - | 3.18 |
| May 17 | vs ATL | W 4-1 | 7.0 | 5 | 1 | 0 | 0 | 2 | 7 | 9 | 8 | 101 | 26 | 70.0 | W(6-2) | - | 2.79 |
| May 11 | @ PIT | W 6-5 | 5.1 | 4 | 2 | 2 | 1 | 4 | 2 | 6 | 11 | 95 | 24 | 50.0 | W(5-2) | - | 3.22 |
| May 5 | @ ATL | W 4-3 | 5.0 | 6 | 2 | 2 | 0 | 2 | 5 | 9 | 6 | 86 | 22 | 50.0 | W(4-2) | - | 3.20 |
| Apr 30 | vs MIL | W 9-3 | 6.0 | 6 | 3 | 3 | 2 | 3 | 1 | 12 | 11 | 90 | 27 | 46.0 | W(3-2) | - | 3.15 |
| Apr 25 | vs PIT | W 1-0 | 5.2 | 3 | 0 | 0 | 0 | 4 | 4 | 9 | 5 | 97 | 22 | 63.0 | W(2-2) | - | 2.86 |
| Apr 20 | @ WSH | L 3-2 | 5.1 | 4 | 0 | 0 | 0 | 5 | 7 | 6 | 7 | 99 | 26 | 62.0 | - | - | 3.57 |
| Apr 15 | @ MIL | W 6-1 | 6.0 | 3 | 1 | 1 | 1 | 3 | 7 | 5 | 7 | 94 | 22 | 66.0 | W(1-2) | - | 4.67 |
| Apr 9 | vs CIN | L 4-0 | 6.0 | 7 | 3 | 3 | 1 | 3 | 5 | 6 | 14 | 92 | 28 | 48.0 | L(0-2) | - | 6.35 |
| Apr 4 | @ PIT | L 12-2 | 5.1 | 6 | 5 | 5 | 3 | 3 | 2 | 7 | 11 | 97 | 23 | 35.0 | L(0-1) | - | 8.44 |