Max Scherzer · Roost| Aug 30 | @ CHW | L 6-3 | 6.2 | 9 | 6 | 5 | 2 | 0 | 11 | 10 | 9 | 113 | 30 | 45.0 | L(15-5) | - | 3.26 |
| Aug 24 | @ MIN | W 13-4 | 5.0 | 7 | 3 | 3 | 0 | 1 | 4 | 10 | 8 | 112 | 24 | 44.0 | W(15-4) | - | 3.13 |
| Aug 19 | @ TB | W 8-6 F/11 | 7.0 | 4 | 4 | 4 | 1 | 3 | 9 | 6 | 10 | 112 | 29 | 59.0 | - | - | 3.07 |
| Aug 14 | vs PIT | W 5-2 | 8.0 | 3 | 0 | 0 | 0 | 2 | 14 | 5 | 7 | 121 | 28 | 88.0 | W(14-4) | - | 2.98 |
| Aug 9 | @ TOR | L 3-2 F/10 | 8.0 | 4 | 1 | 1 | 0 | 0 | 11 | 7 | 9 | 106 | 27 | 81.0 | - | - | 3.13 |
| Aug 4 | @ NYY | L 2-1 | 7.0 | 9 | 2 | 2 | 0 | 3 | 4 | 5 | 18 | 115 | 30 | 52.0 | L(13-4) | - | 3.24 |
| Jul 30 | vs CHW | W 7-2 | 7.0 | 5 | 1 | 1 | 0 | 1 | 6 | 11 | 7 | 98 | 25 | 68.0 | W(13-3) | - | 3.27 |
| Jul 24 | @ LAA | W 6-4 | 7.0 | 6 | 3 | 3 | 0 | 1 | 11 | 6 | 9 | 103 | 28 | 63.0 | W(12-3) | - | 3.37 |
| Jul 19 | vs CLE | L 5-2 | 5.2 | 6 | 2 | 2 | 2 | 4 | 4 | 9 | 10 | 118 | 27 | 49.0 | - | - | 3.34 |
| Jul 15 | vs NLS | W 5-3 | 1.0 | 1 | 0 | 0 | 0 | 0 | 2 | 1 | 1 | 18 | 4 | 0.0 | W(1-0) | - | 0.00 |
| Jul 9 | vs LAD | W 4-1 | 7.0 | 4 | 1 | 1 | 1 | 2 | 7 | 7 | 10 | 101 | 26 | 70.0 | W(11-3) | - | 3.35 |
| Jul 3 | vs TB | W 8-1 | 8.0 | 2 | 1 | 1 | 0 | 1 | 7 | 6 | 13 | 106 | 27 | 80.0 | W(10-3) | - | 3.47 |
| Jun 28 | @ HOU | W 4-3 | 7.0 | 7 | 2 | 2 | 0 | 1 | 13 | 8 | 6 | 112 | 28 | 67.0 | - | - | 3.64 |
| Jun 22 | @ CLE | W 10-4 | 6.0 | 6 | 1 | 1 | 0 | 2 | 8 | 6 | 10 | 114 | 26 | 62.0 | W(9-3) | - | 3.71 |
| Jun 17 | vs KC | L 11-4 | 4.0 | 10 | 10 | 10 | 2 | 1 | 5 | 6 | 11 | 93 | 24 | 6.0 | L(8-3) | - | 3.84 |
| Jun 12 | @ CHW | W 4-0 | 9.0 | 3 | 0 | 0 | 0 | 3 | 8 | 8 | 15 | 113 | 34 | 86.0 | W(8-2) | - | 3.05 |
| Jun 7 | vs BOS | W 8-6 | 6.2 | 11 | 4 | 4 | 1 | 1 | 9 | 9 | 12 | 115 | 31 | 44.0 | W(7-2) | - | 3.38 |
| Jun 1 | @ SEA | L 4-0 | 6.2 | 9 | 4 | 4 | 1 | 0 | 7 | 3 | 17 | 116 | 27 | 47.0 | L(6-2) | - | 3.20 |
| May 27 | @ OAK | W 6-5 | 6.0 | 8 | 5 | 5 | 1 | 2 | 4 | 4 | 17 | 107 | 28 | 38.0 | - | - | 3.00 |
| May 21 | @ CLE | L 11-10 F/13 | 7.0 | 12 | 7 | 7 | 1 | 2 | 5 | 6 | 21 | 113 | 34 | 28.0 | - | - | 2.59 |
| May 16 | @ BOS | W 1-0 | 6.0 | 3 | 0 | 0 | 0 | 4 | 7 | 6 | 6 | 106 | 23 | 69.0 | W(6-1) | - | 1.83 |
| May 10 | vs MIN | W 9-3 | 6.0 | 5 | 3 | 3 | 1 | 4 | 6 | 4 | 13 | 116 | 27 | 52.0 | W(5-1) | - | 2.04 |
| May 5 | vs HOU | W 2-0 | 8.0 | 3 | 0 | 0 | 0 | 1 | 9 | 9 | 8 | 111 | 28 | 84.0 | W(4-1) | - | 1.72 |
| Apr 30 | @ CHW | W 5-1 | 6.0 | 4 | 0 | 0 | 0 | 3 | 7 | 7 | 8 | 105 | 25 | 68.0 | W(3-1) | - | 2.08 |
| Apr 24 | vs CHW | W 7-4 | 6.0 | 7 | 2 | 2 | 1 | 1 | 10 | 5 | 10 | 110 | 26 | 59.0 | W(2-1) | - | 2.45 |
| Apr 19 | vs LAA | W 5-2 | 7.0 | 3 | 1 | 1 | 1 | 2 | 9 | 9 | 5 | 111 | 25 | 74.0 | W(1-1) | - | 2.33 |
| Apr 13 | @ SD | L 5-1 | 5.0 | 4 | 4 | 4 | 1 | 3 | 10 | 5 | 5 | 104 | 23 | 50.0 | L(0-1) | - | 2.70 |
| Apr 8 | @ LAD | L 3-2 F/10 | 7.0 | 8 | 2 | 2 | 1 | 1 | 8 | 9 | 10 | 106 | 28 | 60.0 | - | - | 1.20 |
| Apr 2 | vs KC | W 2-1 F/10 | 8.0 | 4 | 0 | 0 | 0 | 1 | 7 | 6 | 13 | 110 | 27 | 80.0 | - | - | 0.00 |
