Max Scherzer · Roost| Aug 22 | @ HOU | L 4-2 | 5.0 | 7 | 4 | 4 | 0 | 2 | 7 | 9 | 6 | 101 | 24 | 42.0 | L(7-8) | - | 4.12 |
| Aug 17 | @ ATL | L 9-4 | 5.0 | 6 | 9 | 3 | 2 | 1 | 7 | 5 | 10 | 93 | 25 | 37.0 | L(7-7) | - | 4.00 |
| Aug 11 | vs NYM | W 6-2 | 6.2 | 8 | 2 | 2 | 1 | 0 | 8 | 12 | 8 | 118 | 28 | 58.0 | W(7-6) | - | 3.94 |
| Aug 6 | @ PIT | W 11-6 F/12 | 5.1 | 7 | 5 | 5 | 0 | 4 | 5 | 9 | 7 | 100 | 26 | 35.0 | - | - | 4.01 |
| Aug 1 | @ NYM | L 9-6 | 4.0 | 6 | 4 | 4 | 0 | 2 | 4 | 6 | 8 | 86 | 20 | 36.0 | - | - | 3.80 |
| Jul 26 | vs PIT | W 9-0 | 7.0 | 5 | 0 | 0 | 0 | 0 | 8 | 4 | 14 | 109 | 26 | 75.0 | W(6-6) | - | 3.61 |
| Jul 21 | @ COL | W 6-5 | 4.0 | 7 | 4 | 4 | 1 | 1 | 6 | 5 | 8 | 95 | 20 | 37.0 | - | - | 3.86 |
| Jul 8 | vs SD | W 6-2 | 7.0 | 4 | 2 | 2 | 0 | 3 | 9 | 7 | 8 | 108 | 27 | 67.0 | - | - | 3.64 |
| Jul 3 | @ COL | L 5-0 | 6.0 | 6 | 5 | 3 | 1 | 1 | 5 | 8 | 12 | 101 | 26 | 48.0 | L(5-6) | - | 3.73 |
| Jun 28 | vs LAA | L 12-8 | 4.1 | 4 | 8 | 3 | 0 | 3 | 2 | 10 | 6 | 89 | 21 | 32.0 | L(5-5) | - | 3.67 |
| Jun 23 | vs TEX | W 8-2 | 6.0 | 7 | 2 | 2 | 0 | 1 | 7 | 4 | 14 | 119 | 27 | 56.0 | W(5-4) | - | 3.53 |
| Jun 17 | @ KC | W 12-5 | 6.0 | 9 | 2 | 2 | 0 | 3 | 5 | 12 | 10 | 109 | 30 | 48.0 | W(4-4) | - | 3.58 |
| Jun 11 | vs SF | W 2-1 | 7.2 | 3 | 0 | 0 | 0 | 1 | 6 | 6 | 13 | 116 | 27 | 78.0 | W(3-4) | - | 3.63 |
| Jun 6 | @ SD | L 6-4 | 5.0 | 3 | 0 | 0 | 0 | 5 | 6 | 5 | 6 | 104 | 23 | 62.0 | - | - | 4.10 |
| May 31 | vs ATL | L 9-3 | 3.2 | 10 | 8 | 8 | 2 | 3 | 4 | 5 | 11 | 86 | 24 | 10.0 | L(2-4) | - | 4.47 |
| May 26 | vs SD | W 6-5 | 7.0 | 6 | 2 | 2 | 1 | 0 | 10 | 5 | 12 | 103 | 27 | 67.0 | W(2-3) | - | 3.38 |
| May 21 | @ FLA | W 4-3 | 6.0 | 6 | 3 | 3 | 1 | 2 | 10 | 10 | 4 | 109 | 26 | 56.0 | - | - | 3.50 |
| May 16 | @ ATL | W 12-0 | 6.0 | 4 | 0 | 0 | 0 | 3 | 4 | 6 | 9 | 97 | 22 | 65.0 | W(1-3) | - | 3.35 |
| May 10 | vs WAS | W 10-8 | 5.0 | 7 | 4 | 4 | 3 | 3 | 5 | 7 | 10 | 107 | 25 | 39.0 | - | - | 3.98 |
| May 5 | @ LAD | L 3-1 | 6.0 | 4 | 3 | 2 | 0 | 2 | 4 | 11 | 8 | 99 | 25 | 56.0 | L(0-3) | - | 3.38 |
| Apr 30 | @ MIL | L 4-1 | 6.0 | 5 | 0 | 0 | 0 | 1 | 7 | 8 | 8 | 107 | 24 | 68.0 | - | - | 3.48 |
| Apr 25 | vs SF | L 5-3 | 4.2 | 5 | 4 | 4 | 1 | 2 | 6 | 6 | 7 | 98 | 21 | 42.0 | L(0-2) | - | 4.91 |
| Apr 19 | @ SF | L 2-0 | 5.0 | 3 | 1 | 1 | 0 | 4 | 6 | 4 | 8 | 104 | 22 | 59.0 | L(0-1) | - | 3.60 |
| Apr 14 | vs STL | W 7-6 F/10 | 5.0 | 5 | 3 | 3 | 0 | 2 | 1 | 11 | 8 | 83 | 22 | 44.0 | - | - | 5.40 |