Carlos Carrasco · Roost| Sep 2 | vs TB | L 6-4 | 6.1 | 9 | 5 | 5 | 2 | 2 | 9 | 9 | 9 | 107 | 29 | 42.0 | L(16-8) | - | 3.52 |
| Aug 28 | vs MIN | W 8-1 | 7.2 | 4 | 0 | 0 | 0 | 2 | 11 | 9 | 7 | 104 | 29 | 80.0 | W(16-7) | - | 3.38 |
| Aug 22 | @ BOS | L 10-4 | 3.2 | 8 | 6 | 5 | 1 | 1 | 6 | 6 | 7 | 81 | 20 | 28.0 | L(15-7) | - | 3.55 |
| Aug 17 | vs BAL | W 2-1 | 7.0 | 3 | 0 | 0 | 0 | 1 | 6 | 11 | 8 | 116 | 26 | 76.0 | W(15-6) | - | 3.33 |
| Aug 12 | @ CHW | W 9-7 | 7.0 | 3 | 1 | 0 | 0 | 0 | 9 | 9 | 7 | 90 | 25 | 78.0 | W(14-6) | - | 3.50 |
| Aug 7 | vs MIN | L 3-2 | 6.1 | 10 | 3 | 3 | 1 | 1 | 8 | 9 | 10 | 97 | 29 | 0.0 | L(13-6) | - | 3.69 |
| Aug 1 | @ MIN | W 2-0 | 7.1 | 4 | 0 | 0 | 0 | 0 | 10 | 10 | 5 | 101 | 25 | 80.0 | W(13-5) | - | 3.66 |
| Jul 27 | @ DET | W 8-3 | 6.1 | 7 | 3 | 1 | 1 | 2 | 8 | 9 | 8 | 97 | 27 | 57.0 | - | - | 3.89 |
| Jul 21 | @ TEX | W 16-3 | 6.2 | 5 | 2 | 2 | 1 | 1 | 8 | 7 | 8 | 96 | 24 | 63.0 | W(12-5) | - | 4.03 |
| Jul 15 | vs NYY | W 5-2 | 1.0 | 0 | 0 | 0 | 0 | 0 | 2 | 1 | 0 | 14 | 3 | 0.0 | W(11-5) | - | 4.12 |
| Jul 11 | vs CIN | W 19-4 | 5.0 | 5 | 1 | 1 | 0 | 1 | 7 | 3 | 10 | 83 | 21 | 59.0 | W(10-5) | - | 4.16 |
| Jul 6 | vs OAK | W 10-4 | 5.1 | 7 | 3 | 3 | 2 | 0 | 7 | 7 | 7 | 96 | 22 | 49.0 | W(9-5) | - | 4.28 |
| Jun 16 | vs MIN | L 9-3 | 1.1 | 4 | 4 | 4 | 0 | 1 | 2 | 2 | 4 | 39 | 10 | 31.0 | L(8-5) | - | 4.24 |
| Jun 11 | @ CHW | W 4-0 | 7.0 | 2 | 0 | 0 | 0 | 1 | 11 | 7 | 5 | 108 | 25 | 83.0 | W(8-4) | - | 3.90 |
| Jun 6 | vs MIL | W 3-1 | 7.0 | 8 | 1 | 1 | 0 | 1 | 10 | 12 | 5 | 109 | 28 | 66.0 | W(7-4) | - | 4.23 |
| Jun 1 | @ MIN | L 7-4 | 3.2 | 7 | 6 | 6 | 1 | 3 | 2 | 3 | 13 | 71 | 21 | 22.0 | L(6-4) | - | 4.50 |
| May 26 | vs HOU | W 8-6 | 5.2 | 7 | 5 | 5 | 2 | 2 | 8 | 6 | 10 | 108 | 27 | 41.0 | W(6-3) | - | 3.98 |
| May 20 | @ HOU | L 3-1 | 7.2 | 8 | 3 | 3 | 1 | 1 | 6 | 10 | 6 | 106 | 31 | 56.0 | L(5-3) | - | 3.65 |
| May 14 | @ DET | L 6-3 | 6.2 | 6 | 3 | 3 | 1 | 2 | 4 | 12 | 10 | 112 | 28 | 52.0 | L(5-2) | - | 3.66 |
| May 9 | @ MIL | W 6-2 | 9.0 | 5 | 2 | 2 | 0 | 1 | 14 | 8 | 8 | 117 | 31 | 82.0 | W(5-1) | - | 3.61 |
| May 3 | vs TOR | L 13-11 F/11 | 5.1 | 9 | 6 | 6 | 1 | 3 | 7 | 4 | 5 | 113 | 28 | 30.0 | - | - | 10.13 |
| Apr 28 | vs SEA | L 12-4 | 3.0 | 5 | 5 | 4 | 2 | 1 | 4 | 2 | 8 | 64 | 16 | 34.0 | L(4-1) | - | 3.08 |
| Apr 23 | @ BAL | W 2-1 | 7.1 | 6 | 1 | 1 | 0 | 2 | 7 | 6 | 13 | 81 | 28 | 67.0 | W(4-0) | - | 2.31 |
| Apr 18 | @ MIN | L 2-1 F/16 | 7.0 | 3 | 0 | 0 | 0 | 1 | 7 | 7 | 10 | 98 | 25 | 77.0 | - | - | 2.60 |
| Apr 11 | vs DET | W 5-1 | 9.0 | 3 | 1 | 1 | 1 | 2 | 6 | 14 | 9 | 110 | 31 | 81.0 | W(3-0) | - | 3.48 |
| Apr 6 | vs KC | W 3-2 | 6.0 | 5 | 2 | 2 | 0 | 1 | 4 | 9 | 9 | 92 | 23 | 57.0 | W(2-0) | - | 5.40 |
| Mar 31 | @ SEA | W 6-5 | 5.2 | 7 | 5 | 5 | 2 | 0 | 4 | 6 | 13 | 77 | 23 | 39.0 | W(1-0) | - | 7.94 |
