Mike Pelfrey · Roost| Aug 30 | @ MIN | L 11-1 | 1.1 | 5 | 3 | 3 | 1 | 0 | 1 | 5 | 4 | 52 | 10 | 0.0 | - | - | 5.26 |
| Aug 26 | vs DET | L 6-3 | 1.1 | 2 | 1 | 1 | 0 | 1 | 1 | 4 | 1 | 32 | 8 | 0.0 | - | - | 5.07 |
| Aug 22 | vs MIN | L 4-1 | 2.0 | 0 | 0 | 0 | 0 | 1 | 1 | 3 | 1 | 30 | 6 | 0.0 | - | - | 5.05 |
| Aug 18 | @ TEX | W 4-3 | 0.0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 5 | 1 | 0.0 | - | - | 5.15 |
| Aug 17 | @ TEX | L 9-8 | 1.2 | 1 | 0 | 0 | 0 | 1 | 2 | 2 | 2 | 38 | 7 | 0.0 | - | - | 5.15 |
| Aug 13 | vs KC | L 14-6 | 3.0 | 4 | 1 | 1 | 1 | 1 | 3 | 4 | 5 | 62 | 13 | 0.0 | - | - | 5.23 |
| Aug 6 | @ BOS | L 6-3 | 5.2 | 8 | 6 | 6 | 3 | 3 | 2 | 12 | 9 | 89 | 27 | 28.0 | L(3-10) | - | 5.31 |
| Aug 1 | vs TOR | L 8-4 | 5.2 | 7 | 6 | 6 | 2 | 3 | 2 | 8 | 13 | 103 | 27 | 30.0 | L(3-9) | - | 5.04 |
| Jul 27 | vs CHC | L 6-3 | 5.0 | 6 | 5 | 5 | 2 | 2 | 3 | 10 | 7 | 75 | 22 | 36.0 | L(3-8) | - | 4.73 |
| Jul 22 | @ KC | L 7-2 | 5.0 | 2 | 1 | 1 | 0 | 6 | 4 | 5 | 6 | 103 | 21 | 57.0 | - | - | 4.46 |
| Jul 15 | vs SEA | L 4-3 | 4.2 | 4 | 2 | 1 | 1 | 1 | 2 | 10 | 6 | 83 | 19 | 51.0 | - | - | 4.64 |
| Jul 9 | @ COL | L 10-0 | 0.1 | 3 | 3 | 3 | 0 | 1 | 0 | 1 | 0 | 19 | 5 | 0.0 | - | - | - |
| Jul 5 | @ OAK | L 7-4 | 3.1 | 5 | 4 | 4 | 1 | 3 | 5 | 5 | 4 | 99 | 17 | 36.0 | L(3-7) | - | 4.46 |
| Jun 30 | vs TEX | W 8-7 | 5.0 | 8 | 5 | 5 | 2 | 2 | 2 | 10 | 8 | 101 | 23 | 31.0 | - | - | 4.13 |
| Jun 23 | vs OAK | L 3-0 | 4.2 | 4 | 3 | 3 | 2 | 5 | 4 | 7 | 7 | 106 | 23 | 43.0 | L(3-6) | - | 3.73 |
| Jun 17 | @ TOR | W 5-2 | 6.0 | 4 | 1 | 1 | 0 | 0 | 5 | 9 | 7 | 86 | 21 | 65.0 | W(3-5) | - | 3.56 |
| Jun 14 | vs BAL | L 10-6 | 1.0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 2 | 14 | 3 | 0.0 | - | - | 3.81 |
| Jun 12 | vs BAL | W 10-7 | 3.2 | 6 | 2 | 2 | 0 | 5 | 2 | 6 | 6 | 83 | 20 | 38.0 | - | - | 3.88 |
| Jun 7 | @ TB | L 3-1 | 5.1 | 6 | 3 | 2 | 0 | 3 | 4 | 9 | 10 | 96 | 27 | 47.0 | L(2-5) | - | 3.80 |
| May 31 | vs BOS | L 4-1 | 5.0 | 2 | 0 | 0 | 0 | 2 | 5 | 8 | 4 | 83 | 19 | 66.0 | - | - | 3.86 |
| May 26 | vs DET | W 8-2 | 5.0 | 4 | 2 | 1 | 1 | 1 | 7 | 7 | 7 | 86 | 22 | 59.0 | W(2-4) | - | 4.41 |
| May 20 | @ SEA | W 16-1 | 6.0 | 4 | 1 | 1 | 0 | 0 | 3 | 9 | 8 | 77 | 20 | 63.0 | W(1-4) | - | 4.85 |
| May 15 | @ LAA | L 5-3 | 4.2 | 3 | 4 | 4 | 2 | 3 | 2 | 8 | 7 | 100 | 20 | 41.0 | L(0-4) | - | 5.70 |
| May 9 | vs MIN | L 7-2 | 4.2 | 5 | 3 | 3 | 1 | 1 | 2 | 8 | 9 | 95 | 21 | 43.0 | L(0-3) | - | 5.21 |
| May 3 | @ KC | L 6-1 | 5.1 | 5 | 3 | 3 | 0 | 1 | 1 | 7 | 12 | 82 | 21 | 46.0 | L(0-2) | - | 5.02 |
| Apr 28 | @ DET | W 7-3 | 4.2 | 6 | 3 | 3 | 0 | 4 | 2 | 9 | 8 | 90 | 23 | 38.0 | - | - | 5.00 |
| Apr 22 | vs CLE | L 7-0 | 4.1 | 4 | 4 | 2 | 1 | 1 | 1 | 6 | 11 | 81 | 20 | 43.0 | L(0-1) | - | 4.15 |