Mike Pelfrey · Roost| Jul 3 | @ TB | W 5-1 | 6.1 | 6 | 1 | 1 | 0 | 3 | 3 | 10 | 5 | 84 | 27 | 57.0 | - | - | 1.42 |
| Jun 28 | vs MIA | W 7-5 | 5.1 | 12 | 4 | 4 | 1 | 1 | 1 | 18 | 8 | 100 | 28 | 28.0 | W(2-7) | - | 5.02 |
| Jun 24 | vs CLE | L 7-5 | 4.1 | 3 | 0 | 0 | 0 | 0 | 2 | 5 | 8 | 48 | 15 | 0.0 | - | - | 4.91 |
| Jun 20 | vs SEA | W 8-7 F/12 | 5.0 | 12 | 6 | 6 | 2 | 1 | 3 | 12 | 9 | 92 | 25 | 21.0 | - | - | 5.19 |
| Jun 15 | @ CHW | L 5-3 | 6.0 | 7 | 4 | 4 | 0 | 2 | 1 | 11 | 12 | 90 | 28 | 41.0 | L(1-7) | - | 4.79 |
| Jun 10 | @ NYY | L 4-0 | 6.2 | 6 | 4 | 3 | 0 | 5 | 2 | 15 | 6 | 111 | 28 | 45.0 | L(1-6) | - | 4.68 |
| Jun 4 | vs CHW | W 7-4 | 6.0 | 5 | 2 | 2 | 0 | 3 | 3 | 10 | 9 | 96 | 26 | 54.0 | W(1-5) | - | 4.76 |
| May 29 | @ OAK | L 4-2 | 5.2 | 6 | 3 | 0 | 0 | 2 | 3 | 8 | 12 | 95 | 25 | 52.0 | L(0-5) | - | 4.96 |
| May 23 | vs PHI | W 5-4 | 6.0 | 11 | 4 | 4 | 2 | 0 | 3 | 12 | 11 | 94 | 26 | 37.0 | - | - | 5.55 |
| May 17 | vs MIN | W 7-2 | 5.1 | 7 | 2 | 2 | 2 | 1 | 3 | 7 | 13 | 96 | 24 | 48.0 | - | - | 5.49 |
| May 12 | @ BAL | L 7-5 | 5.1 | 5 | 2 | 2 | 0 | 2 | 5 | 8 | 8 | 96 | 23 | 53.0 | - | - | 5.80 |
| May 7 | vs TEX | L 10-5 | 5.0 | 7 | 5 | 5 | 3 | 0 | 3 | 9 | 9 | 84 | 21 | 36.0 | - | - | 6.23 |
| May 1 | @ MIN | W 6-5 | 4.0 | 8 | 5 | 5 | 0 | 3 | 3 | 10 | 7 | 98 | 23 | 26.0 | - | - | 5.68 |
| Apr 26 | vs OAK | L 5-1 | 6.2 | 9 | 5 | 5 | 1 | 0 | 1 | 10 | 17 | 100 | 28 | 37.0 | L(0-4) | - | 4.64 |
| Apr 21 | @ KC | L 4-0 | 5.0 | 8 | 4 | 3 | 1 | 5 | 2 | 9 | 10 | 104 | 26 | 34.0 | L(0-3) | - | 3.68 |
| Apr 15 | @ HOU | L 1-0 | 6.0 | 5 | 1 | 1 | 0 | 6 | 3 | 12 | 5 | 104 | 26 | 55.0 | L(0-2) | - | 2.79 |
| Apr 9 | vs NYY | L 8-4 | 3.2 | 7 | 6 | 2 | 1 | 1 | 3 | 7 | 8 | 74 | 19 | 33.0 | L(0-1) | - | 4.91 |