Mike Pelfrey · Roost| Aug 18 | @ NYY | L 8-4 | 5.1 | 5 | 1 | 1 | 0 | 1 | 4 | 4 | 13 | 104 | 23 | 57.0 | - | - | 3.62 |
| Aug 12 | vs TEX | W 11-1 | 7.0 | 4 | 1 | 1 | 0 | 1 | 4 | 11 | 9 | 101 | 25 | 68.0 | W(6-7) | - | 3.70 |
| Aug 7 | @ CLE | W 10-9 | 3.2 | 9 | 7 | 4 | 0 | 1 | 2 | 7 | 11 | 74 | 21 | 22.0 | - | - | 3.84 |
| Aug 2 | vs SEA | L 4-1 F/11 | 8.0 | 4 | 0 | 0 | 0 | 1 | 3 | 16 | 7 | 102 | 27 | 76.0 | - | - | 3.65 |
| Jul 28 | vs PIT | L 8-7 | 5.1 | 5 | 3 | 2 | 0 | 2 | 3 | 10 | 10 | 87 | 26 | 49.0 | - | - | 3.92 |
| Jul 22 | @ LAA | L 5-2 | 6.0 | 9 | 4 | 2 | 1 | 1 | 1 | 11 | 13 | 79 | 27 | 42.0 | L(5-7) | - | 3.94 |
| Jul 9 | vs DET | L 4-2 | 7.2 | 8 | 4 | 4 | 1 | 0 | 4 | 13 | 11 | 110 | 28 | 51.0 | L(5-6) | - | 4.00 |
| Jul 4 | @ KC | W 5-3 | 4.0 | 7 | 3 | 3 | 0 | 3 | 3 | 8 | 7 | 75 | 21 | 36.0 | - | - | 3.94 |
| Jun 29 | @ CIN | L 11-7 | 2.0 | 9 | 8 | 8 | 0 | 3 | 1 | 5 | 8 | 68 | 17 | 4.0 | L(5-5) | - | 3.81 |
| Jun 23 | vs CHW | L 6-2 | 6.2 | 10 | 3 | 3 | 0 | 3 | 4 | 19 | 6 | 112 | 32 | 43.0 | L(5-4) | - | 3.06 |
| Jun 18 | vs STL | W 2-1 | 8.0 | 4 | 1 | 1 | 1 | 1 | 3 | 10 | 14 | 103 | 28 | 72.0 | - | - | 2.97 |
| Jun 13 | @ TEX | L 11-7 | 3.2 | 11 | 8 | 8 | 1 | 3 | 0 | 12 | 7 | 65 | 22 | 4.0 | L(5-3) | - | 3.18 |
| Jun 7 | vs MIL | W 2-0 | 8.0 | 8 | 0 | 0 | 0 | 1 | 7 | 11 | 11 | 105 | 30 | 72.0 | W(5-2) | - | 2.28 |
| Jun 2 | @ BOS | L 1-0 | 7.0 | 6 | 1 | 1 | 0 | 2 | 1 | 13 | 11 | 99 | 27 | 60.0 | L(4-2) | - | 2.59 |
| May 26 | vs BOS | W 2-1 | 7.0 | 5 | 1 | 1 | 0 | 1 | 4 | 9 | 11 | 100 | 25 | 66.0 | W(4-1) | - | 2.77 |
| May 20 | @ PIT | W 4-3 F/13 | 6.0 | 5 | 1 | 1 | 0 | 0 | 5 | 11 | 5 | 92 | 22 | 63.0 | - | - | 3.00 |
| May 14 | @ DET | L 13-1 | 4.2 | 10 | 5 | 4 | 1 | 2 | 1 | 12 | 12 | 95 | 27 | 25.0 | L(3-1) | - | 3.23 |
| May 8 | @ CLE | W 9-3 | 7.0 | 6 | 2 | 2 | 0 | 2 | 0 | 18 | 9 | 105 | 29 | 55.0 | W(3-0) | - | 2.62 |
| May 3 | vs CHW | W 13-3 | 3.1 | 5 | 2 | 2 | 0 | 2 | 1 | 6 | 6 | 61 | 18 | 41.0 | - | - | 2.63 |
| Apr 28 | vs DET | W 3-2 | 7.0 | 3 | 2 | 1 | 0 | 2 | 7 | 8 | 9 | 109 | 26 | 70.0 | W(2-0) | - | 2.25 |
| Apr 22 | @ KC | W 3-0 | 7.0 | 5 | 0 | 0 | 0 | 2 | 4 | 12 | 8 | 99 | 28 | 69.0 | W(1-0) | - | 2.65 |
| Apr 17 | vs CLE | W 3-2 F/11 | 5.0 | 3 | 1 | 1 | 0 | 4 | 2 | 8 | 6 | 88 | 21 | 55.0 | - | - | 4.50 |
| Apr 11 | @ CHW | L 5-4 | 5.0 | 7 | 4 | 4 | 2 | 1 | 2 | 13 | 6 | 80 | 23 | 38.0 | - | - | 7.20 |
