Carlos Manuel Villanueva · Roost| Aug 3 | @ TB | L 9-1 | 2.2 | 9 | 8 | 8 | 3 | 0 | 1 | 7 | 10 | 69 | 19 | 9.0 | L(6-3) | - | 4.24 |
| Jul 28 | vs BAL | W 8-5 | 5.0 | 6 | 4 | 4 | 2 | 2 | 1 | 5 | 16 | 84 | 24 | 38.0 | W(6-2) | - | 3.60 |
| Jul 23 | @ TEX | L 5-4 | 5.2 | 10 | 3 | 3 | 0 | 0 | 1 | 7 | 19 | 105 | 27 | 38.0 | - | - | 3.40 |
| Jul 17 | vs NYY | L 7-2 | 6.0 | 8 | 5 | 5 | 0 | 1 | 6 | 5 | 15 | 98 | 27 | 41.0 | L(5-2) | - | 3.31 |
| Jul 7 | @ CLE | L 5-4 | 6.0 | 6 | 0 | 0 | 0 | 2 | 7 | 5 | 12 | 110 | 27 | 65.0 | - | - | 2.99 |
| Jul 2 | vs PHI | L 5-3 | 6.2 | 5 | 3 | 3 | 0 | 4 | 3 | 8 | 14 | 106 | 29 | 51.0 | - | - | 3.24 |
| Jun 25 | @ STL | W 6-3 | 6.0 | 5 | 2 | 2 | 0 | 1 | 3 | 7 | 12 | 96 | 23 | 56.0 | W(5-1) | - | 3.15 |
| Jun 19 | @ CIN | L 2-1 | 7.0 | 7 | 2 | 2 | 1 | 0 | 3 | 7 | 18 | 89 | 28 | 58.0 | L(4-1) | - | 3.17 |
| Jun 14 | vs BAL | W 6-5 F/11 | 6.0 | 7 | 3 | 3 | 0 | 2 | 3 | 10 | 11 | 98 | 26 | 47.0 | - | - | 3.25 |
| Jun 8 | @ KC | W 9-8 | 7.0 | 6 | 4 | 4 | 1 | 1 | 5 | 9 | 12 | 102 | 27 | 53.0 | W(4-0) | - | 3.09 |
| Jun 3 | @ BAL | W 8-4 | 5.1 | 6 | 2 | 2 | 0 | 1 | 0 | 10 | 11 | 90 | 24 | 47.0 | W(3-0) | - | 2.72 |
| May 28 | vs CHW | W 9-8 F/14 | 5.0 | 8 | 6 | 5 | 1 | 1 | 4 | 9 | 11 | 82 | 25 | 32.0 | - | - | 2.62 |
| May 23 | @ NYY | W 7-3 | 5.0 | 2 | 1 | 1 | 0 | 1 | 5 | 4 | 9 | 75 | 19 | 63.0 | W(2-0) | - | 1.53 |
| May 18 | vs TB | L 6-5 | 2.0 | 1 | 0 | 0 | 0 | 0 | 4 | 2 | 0 | 25 | 6 | 0.0 | - | - | 1.48 |
| May 15 | @ MIN | W 11-3 | 1.0 | 0 | 0 | 0 | 0 | 1 | 2 | 1 | 0 | 21 | 4 | 0.0 | - | - | 1.61 |
| May 10 | vs BOS | W 7-6 F/10 | 1.0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 3 | 16 | 4 | 0.0 | W(1-0) | - | 1.69 |
| May 7 | vs DET | L 9-0 | 4.2 | 4 | 1 | 1 | 0 | 1 | 4 | 3 | 10 | 69 | 18 | 0.0 | - | - | 1.77 |
| May 1 | @ NYY | L 5-2 | 1.0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 2 | 7 | 3 | 0.0 | - | - | 1.72 |
| Apr 27 | @ TEX | L 7-6 | 3.1 | 0 | 0 | 0 | 0 | 1 | 0 | 7 | 3 | 51 | 11 | 0.0 | - | - | 1.84 |
| Apr 23 | vs TB | L 6-4 | 0.2 | 2 | 2 | 2 | 1 | 1 | 0 | 0 | 4 | 17 | 5 | 0.0 | - | - | 2.38 |
| Apr 19 | vs NYY | W 6-5 F/10 | 1.0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 2 | 15 | 3 | 0.0 | - | - | 0.84 |
| Apr 16 | @ BOS | L 4-1 | 3.0 | 0 | 0 | 0 | 0 | 2 | 2 | 1 | 5 | 42 | 10 | 0.0 | - | - | 0.93 |
| Apr 11 | @ SEA | L 8-7 | 1.0 | 1 | 1 | 1 | 1 | 1 | 2 | 1 | 1 | 23 | 5 | 0.0 | - | - | 1.35 |
| Apr 9 | @ LAA | L 6-5 F/14 | 2.0 | 0 | 0 | 0 | 0 | 1 | 3 | 2 | 0 | 27 | 6 | 0.0 | - | - | 0.00 |
| Apr 5 | vs OAK | W 7-6 F/10 | 2.2 | 0 | 0 | 0 | 0 | 2 | 3 | 1 | 3 | 34 | 9 | 0.0 | - | - | 0.00 |
| Apr 1 | vs MIN | W 13-3 | 1.0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 2 | 10 | 3 | 0.0 | - | - | 0.00 |